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Proteomic analysis of Staphylococcus aureus biofilm cells grown under physiologically relevant fluid shear stress conditions
Background: The biofilm forming bacterium Staphylococcus aureus is responsible for maladies ranging from severe skin infection to major diseases such as bacteremia, endocarditis and osteomyelitis. A flow displacement system ...
Proteome Analyses of Staphylococcus aureus Biofilm at Elevated Levels of NaCl
(OMICS Publishing Group, 2015-10)
Our studies demonstrate that sodium chloride (NaCl) induces changes in biofilm, mediated by increased production of polysaccharides intercellular adhesion (PIA). We identified 12 proteins that showed higher abundance in ...
Blood Serum Affects Polysaccharide Production and Surface Protein Expression in S. Aureus
(Juniper Publishers, 2017-01)
S. aureus biofilm serves a major role in pathogenesis. Two of the major components of bacterial biofilm are Polysaccharides intercellular adhesions (PIA) and surface proteins. It is not known how PIA and surface proteins ...