Now showing items 68-87 of 187

    • Flavin oxidation in flavin dependent N-monooxygenase 

      Sobrado, Pablo; Robinson, Reeder; Klancher, Catherine; Rodriguez, Pedro (2019-01-02)
    • Fluorescence Polarization Binding Assay for Aspergillus fumigatus Virulence Factor UDP-Galactopyranose Mutase 

      Qi, Jun; Oppenheimer, Michelle; Sobrado, Pablo (Hindawi, 2011-08-21)
      Aspergillus fumigatus is an opportunistic human pathogenic fungus responsible for deadly lung infections in immunocompromised individuals. Galactofuranose (Galf) residues are essential components of the cell wall and play ...
    • From L-Dopa to Dihydroxyphenylacetaldehyde: A Toxic Biochemical Pathway Plays a Vital Physiological Function in Insects 

      Vavricka, Christopher; Han, Qian; Huang, Yongping; Erickson, Sara M.; Harich, Kim; Christensen, Bruce M.; Li, Jianyong (PLOS, 2011-01-24)
      One protein in Aedes aegypti, classified into the aromatic amino acid decarboxylase (AAAD) family based on extremely high sequence homology (∼70%) with dopa decarboxylase (Ddc), was biochemically investigated. Our data ...
    • Functional analysis of the promoter of an early zygotic gene KLC2 in Aedes aegypti 

      Hu, Wanqi; Tu, Zhijian J (2018-12-24)
      Abstract Background Aedes aegypti is an important mosquito vector that transmits arboviruses that cause devastating diseases including Zika, dengue fever, yellow fever and ...
    • Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum 

      Elahi, Rubayet; Ray, W. Keith; Dapper, Christie; Dalal, Seema; Helm, Richard F.; Klemba, Michael (2019-11-26)
      Enzymes of the serine hydrolase superfamily are ubiquitous, highly versatile catalysts that mediate a wide variety of metabolic reactions in eukaryotic cells, while also being amenable to selective inhibition. We have ...
    • FusoPortal: an Interactive Repository of Hybrid MinIONSequenced Fusobacterium Genomes Improves Gene Identification and Characterization 

      Sanders, Blake E.; Umana, Ariana; Lemkul, Justin A.; Slade, Daniel J. (American Society for Microbiology, 2018-07-05)
      Here we present FusoPortal, an interactive repository of Fusobacterium genomes that were sequenced using a hybrid MinION long-read sequencing pipeline, followed by assembly and annotation using a diverse portfolio of ...
    • Genetic diversity of Plasmodium vivax in clinical isolates from Bangladesh 

      Kibria, Mohammad G; Elahi, Rubayet; Mohon, Abu N; Khan, Wasif A; Haque, Rashidul; Alam, Mohammad S (2015-07-11)
      Background Plasmodium vivax is the second most prevalent human malaria parasite in Bangladesh; however, there are no data of its genetic diversity. Several molecular markers are available where Pvcsp, Pvmsp 1 and Pvmsp 3α ...
    • Genetic Reporter System for Positioning of Proteins at the Bacterial Pole 

      Fixen, Kathryn R.; Janakiraman, Anuradha; Garrity, Sean; Slade, Daniel J.; Gray, Andrew N.; Karahan, Nilay; Hochschild, Ann; Goldberg, Marcia B. (2012)
      Spatial organization within bacteria is fundamental to many cellular processes, although the basic mechanisms underlying localization of proteins to specific sites within bacteria are poorly understood. The study of protein ...
    • Genetic resources for advanced biofuel production described with the Gene Ontology 

      Torto-Alalibo, T; Purwantini, E; Lomax, J; Setubal, JC; Mukhopadhyay, B; Tyler, BM (Frontiers Research Foundation, 2014-10-10)
    • Genetic resources for methane production from biomass described with the Gene Ontology 

      Purwantini, E; Torto-Alalibo, T; Lomax, J; Setubal, JC; Tyler, BM; Mukhopadhyay, B (Frontiers Research Foundation, 2014-12-03)
    • A Genetic System for Methanocaldococcus jannaschii: An Evolutionary Deeply Rooted Hyperthermophilic Methanarchaeon 

      Susanti, Dwi; Frazier, Mary C.; Mukhopadhyay, Biswarup (Frontiers, 2019-07-03)
      Phylogenetically deeply rooted methanogens belonging to the genus of Methanocaldococcus living in deep-sea hydrothermal vents derive energy exclusively from hydrogenotrophic methanogenesis, one of the oldest respiratory ...
    • Genome Landscape and Evolutionary Plasticity of Chromosomes in Malaria Mosquitoes 

      Xia, Ai; Sharakhova, Maria V.; Leman, Scotland C.; Tu, Zhijian; Bailey, Jeffrey A.; Smith, Christopher D.; Sharakhov, Igor V. (PLOS, 2010-05-12)
      Background: Nonrandom distribution of rearrangements is a common feature of eukaryotic chromosomes that is not well understood in terms of genome organization and evolution. In the major African malaria vector Anopheles ...
    • Genome-wide transcriptome analyses of developing seeds from low and normal phytic acid soybean lines 

      Redekar, Neelam R.; Biyashev, Ruslan M.; Jensen, Roderick V.; Helm, Richard F.; Grabau, Elizabeth A.; Maroof, M. A. Saghai (2015-12-18)
      Background Low phytic acid (lpa) crops are potentially eco-friendly alternative to conventional normal phytic acid (PA) crops, improving mineral bioavailability in monogastric animals as well as decreasing phosphate ...
    • Genomic composition and evolution of Aedes aegypti chromosomes revealed by the analysis of physically mapped supercontigs 

      Timoshevskiy, Vladimir A.; Kinney, Nicholas A.; deBruyn, Becky S.; Mao, Chunhong; Tu, Zhijian; Severson, D. W.; Sharakhov, Igor V.; Sharakhova, Maria V. (Biomed Central Ltd, 2014-04-14)
      Background An initial comparative genomic study of the malaria vector Anopheles gambiae and the yellow fever mosquito Aedes aegypti revealed striking differences in the genome assembly size and in the abundance of transposable ...
    • Genomic insights into the Ixodes scapularis tick vector of Lyme disease 

      Gulia-Nuss, Monika; Nuss, Andrew B.; Meyer, Jason M.; Sonenshine, Daniel E.; Roe, R. Michael; Waterhouse, Robert M.; Sattelle, David B.; de la Fuente, Jose; Ribeiro, Jose M.; Megy, Karine; Thimmapuram, Jyothi; Miller, Jason R.; Walenz, Brian P.; Koren, Sergey; Hostetler, Jessica B.; Thiagarajan, Mathangi; Joardar, Vinita S.; Hannick, Linda I.; Bidwell, Shelby; Hammond, Martin P.; Young, Sarah; Zeng, Qiandong; Abrudan, Jenica L.; Almeida, Francisca C.; Ayllon, Nieves; Bhide, Ketaki; Bissinger, Brooke W.; Bonzon-Kulichenko, Elena; Buckingham, Steven D.; Caffrey, Daniel R.; Caimano, Melissa J.; Croset, Vincent; Driscoll, Timothy; Gilbert, Don; Gillespie, Joseph J.; Giraldo-Calderon, Gloria I.; Grabowski, Jeffrey M.; Jiang, David; Khalil, Sayed M. S.; Kim, Donghun; Kocan, Katherine M.; Koci, Juraj; Kuhn, Richard J.; Kurtti, Timothy J.; Lees, Kristin; Lang, Emma G.; Kennedy, Ryan C.; Kwon, Hyeogsun; Perera, Rushika; Qi, Yumin; Radolf, Justin D.; Sakamoto, Joyce M.; Sanchez-Gracia, Alejandro; Severo, Maiara S.; Silverman, Neal; Simo, Ladislav; Tojo, Marta; Tornador, Cristian; Van Zee, Janice P.; Vazquez, Jesus; Vieira, Filipe G.; Villar, Margarita; Wespiser, Adam R.; Yang, Yunlong; Zhu, Jiwei; Arensburger, Peter; Pietrantonio, Patricia V.; Barker, Stephen C.; Shao, Renfu; Zdobnov, Evgeny M.; Hauser, Frank; Grimmelikhuijzen, Cornelis J. P.; Park, Yoonseong; Rozas, Julio; Benton, Richard; Pedra, Joao H. F.; Nelson, David R.; Unger, Maria F.; Tubio, Jose M. C.; Tu, Zhijian; Robertson, Hugh M.; Shumway, Martin; Sutton, Granger; Wortman, Jennifer R.; Lawson, Daniel; Wikel, Stephen K.; Nene, Vishvanath M.; Fraser, Claire M.; Collins, Frank H.; Birren, Bruce; Nelson, Karen E.; Caler, Elisabet; Hill, Catherine A. (Springer Nature, 2016-02)
      Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic ...
    • GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro 

      Wang, Aihua; Luo, Jing; Moore, William; Alkhalidy, Hana; Wu, Ling; Zhang, Jinhua; Zhen, Wei; Wang, Yao; Clegg, Deborah J.; Xu, Bin; Cheng, Zhiyong; McMillan, Ryan P.; Hulver, Matthew W.; Liu, Dongmin (Nature Publishing Group, 2016-10-04)
    • GUY1 confers complete female lethality and is a strong candidate for a male-determining factor in Anopheles stephensi 

      Criscione, Frank; Qi, Yumin; Tu, Zhijian (eLife, 2016-09-20)
      Despite their importance in sexual differentiation and reproduction, Y chromosome genes are rarely described because they reside in repeat-rich regions that are difficult to study. Here, we show that Guy1, a unique Y ...
    • Guy1, a Y-linked embryonic signal, regulates dosage compensation in Anopheles stephensi by increasing X gene expression 

      Qi, Yumin; Wu, Yang; Saunders, Randy; Chen, Xiao-Guang; Mao, Chunhong; Biedler, James Kite; Tu, Zhijian Jake (2019-03-19)
      We previously showed that Guy1, a primary signal expressed from the Y chromosome, is a strong candidate for a male-determining factor that confers female-specific lethality in Anopheles stephensi (Criscione et al., 2016). ...
    • The hepatocyte proteome in organotypic rat liver models and the influence of the local microenvironment 

      Vu, Lucas T.; Orbach, Sophia M.; Ray, W. Keith; Cassin, Margaret E.; Rajagopalan, Padmavathy; Helm, Richard F. (Biomed Central Ltd, 2017-06-20)
      Background: Liver models that closely mimic the in vivo microenvironment are useful for understanding liver functions, capabilities, and intercellular communication processes. Three-dimensional (3D) liver models assembled ...
    • Honeybees in a virtual reality environment learn unique combinations of colour and shape 

      Rusch, C; Roth, E; Vinauger, C; Riffell, JA (Company Of Biologists Ltd, 2017-12-15)
      Honeybees arewell-known models for the study of visual learning and memory. Whereas most of our knowledge of learned responses comes from experiments using free-flying bees, a tethered preparation would allow fine-scale ...