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Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells
Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the ...
Virtual methylome dissection facilitated by single-cell analyses
Abstract Background Numerous cell types can be identified within plant tissues and animal organs, and the epigenetic modifications underlying such enormous cellular heterogeneity are just beginning to be understood. It ...