Now showing items 1-10 of 112
Global expansion and redistribution of Aedes-borne virus transmission risk with climate change
Forecasting the impacts of climate change on Aedes-borne viruses, especially dengue, chikungunya, and Zika is a key component of public health preparedness. We apply an empirically parameterized model of viral transmission ...
Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma
(Springer Nature, 2018-01-19)
Glioma is a unique neoplastic disease that develops exclusively in the central nervous system (CNS) and rarely metastasizes to other tissues. This feature strongly implicates the tumor-host CNS microenvironment in gliomagenesis ...
'Cut from the same cloth': Shared microsatellite variants among cancers link to ectodermal tissues-neural tube and crest cells
(Impact Journals Llc, 2015-09-08)
Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells
Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the ...
A Bayesian Analysis of Copy Number Variations in Array Comparative Genomic Hybridization Data
(OMICS International, 2015-09-25)
Array Comparative Genomic Hybridization (CGH) has been widely used for detecting genomic copy number variations (CNVs). The central goal of array CGH data analysis is to accurately detect homogeneous regions of log intensity ...
The effect of temporal aggregation level in social network monitoring
Social networks have become ubiquitous in modern society, which makes social network monitoring a research area of significant practical importance. Social network data consist of social interactions between pairs of ...
Penalized Variable Selection Procedure for Cox Models with Semiparametric Relative Risk
(Inst Mathematical Statistics, 2010-08-01)
Nonparametric Bayesian clustering to detect bipolar methylated genomic loci
(Biomed Central Ltd, 2015-01-16)
Linked within-host and between-host models and data for infectious diseases: a systematic review
The observed dynamics of infectious diseases are driven by processes across multiple scales. Here we focus on two: within-host, that is, how an infection progresses inside a single individual (for instance viral and immune ...
Modeling Temperature Effects on Population Density of the Dengue Mosquito Aedes aegypti
Mosquito density plays an important role in the spread of mosquito-borne diseases such as dengue and Zika. While it remains very challenging to estimate the density of mosquitoes, modelers have tried different methods to ...