Now showing items 1-3 of 3
Genome mapping and characterization of the Anopheles gambiae heterochromatin
(Biomed Central Ltd, 2010-08-04)
Background Heterochromatin plays an important role in chromosome function and gene regulation. Despite the availability of polytene chromosomes and genome sequence, the heterochromatin of the major malaria vector Anopheles ...
Performance evaluation of indel calling tools using real short-read data
(Biomed Central Ltd, 2015-08-19)
Background Insertion and deletion (indel), a common form of genetic variation, has been shown to cause or contribute to human genetic diseases and cancer. With the advance of next-generation sequencing technology, many ...
Arm-specific dynamics of chromosome evolution in malaria mosquitoes
(Biomed Central Ltd, 2011-04-07)
Background: The malaria mosquito species of subgenus Cellia have rich inversion polymorphisms that correlate with environmental variables. Polymorphic inversions tend to cluster on the chromosomal arms 2R and 2L but not ...