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Transcriptomic Analysis of Hepatic Cells in Multicellular Organotypic Liver Models
(Springer Nature, 2018-07-27)
Liver homeostasis requires the presence of both parenchymal and non-parenchymal cells (NPCs). However, systems biology studies of the liver have primarily focused on hepatocytes. Using an organotypic three-dimensional (3D) ...
Generalized Likelihood Uncertainty Estimation and Markov Chain Monte Carlo Simulation to Prioritize TMDL Pollutant Allocations
(2018-12)
This study presents a probabilistic framework that considers both the water quality improvement capability and reliability of alternative total maximum daily load (TMDL) pollutant allocations. Generalized likelihood ...
Two-phase Monte Carlo simulation for partitioning the effects of epistemic and aleatory uncertainty in TMDL modeling
(American Society of Civil Engineers (ASCE), 2018-10-29)
A two-phase Monte Carlo simulation (TPMCS) uncertainty analysis framework is used to analyze epistemic and aleatory uncertainty associated with simulated exceedances of an in-stream fecal coliform (FC) water quality criterion ...
The effect of temporal aggregation level in social network monitoring
(PLOS, 2018-12-19)
Social networks have become ubiquitous in modern society, which makes social network monitoring a research area of significant practical importance. Social network data consist of social interactions between pairs of ...
Profile monitoring based quality control method for fused deposition modeling process
(Springer New York LLC, 2018-05-26)
In order to monitor the quality of parts in printing, the methodology to monitor the geometric quality of the printed parts in fused deposition modeling process is researched. A non-contact measurement method based on ...
Can long-term historical data from electronic medical records improve surveillance for epidemics of acute respiratory infections? A systematic evaluation
(PLOS, 2018-01-31)
Background As the deployment of electronic medical records (EMR) expands, so is the availability of long-term datasets that could serve to enhance public health surveillance. We hypothesized that EMR-based surveillance ...
Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma
(Springer Nature, 2018-01-19)
Glioma is a unique neoplastic disease that develops exclusively in the central nervous system (CNS) and rarely metastasizes to other tissues. This feature strongly implicates the tumor-host CNS microenvironment in gliomagenesis ...
Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells
(PLOS, 2018-03)
Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the ...
COREMIC: a web-tool to search for a niche associated CORE MICrobiome
(PeerJ, 2018-02-15)
Microbial diversity on earth is extraordinary, and soils alone harbor thousands of species per, gram of soil. Understanding how this diversity is sorted and selected into habitat niches is a major focus of ecology and ...