Browsing Faculty Works, Department of Biomedical Sciences and Pathobiology by Title
Now showing items 47-66 of 247
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Dehydroepiandrosterone protects vascular endothelial cells against apoptosis through a G alpha(i) protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression
(Endocrine Society, 2007-07)The adrenal steroid dehydroepiandrosterone (DHEA) may improve vascular function, but the mechanism is unclear. In the present study, we show that DHEA significantly increased cell viability, reduced caspase-3 activity, and ... -
Descriptions of two new species of coccidia (Protozoa : Eimeriidae) and redescriptions of Eimeria ivensae and Eimeria odocoilei from captive white-tailed deer, Odocoileus virginianus
(American Society of Parasitology, 1999-12)Two new species of Eimeria were observed in the feces of captive white-tailed deer fawns, Odocoileus virginianus, from Alabama. The first new species was easily recognized because of its small size. Sporulated oocysts are ... -
Detection of Hammondia heydorni-like organisms and their differentiation from Neospora caninum using random-amplified polymorphic DNA-polymerase chain reaction
(American Society of Parasitology, 2003-10)Neospora caninum and Hammondia heydorni are morphologically and phylogenetically related coccidians that are found in dogs. New diagnostic genetic loci, based on random-amplified polymorphic DNA-polymerase chain reaction ... -
Determination of the activity of diclazuril against Sarcocystis neurona and Sarcocystis falcatula in cell cultures
(American Society of Parasitology, 2000-02)Diclazuril is a benzeneacetonitril anticoccidial that has excellent activity against the extraintestinal stages of Toxoplasma gondii and Neospora caninum. It also is highly active against intestinal coccidia of poultry. ... -
Development and evaluation of two subunit vaccine candidates containing antigens of hepatitis E virus, rotavirus, and astrovirus
(Springer Nature, 2016-05-19)Hepatitis E virus (HEV), rotavirus (RV), and astrovirus (AstV) are important pathogens that transmit through a common fecal-oral route, causing hepatitis (HEV) and gastroenteritis (RV and AstV) respectively in humans. In ... -
Development and ultrastructure of cystoisospora canis nemeseri, 1959 (syn. isospora canis) monozoic cysts in two noncanine cell lines
(American Society of Parasitology, 2009-08)Cystoisospora canis is a coccidial parasite of the intestinal tract that can cause severe disease in dogs. Clinical Signs include watery diarrhea, vomiting, fever, and weight loss. Extraintestinal stages of Cystoisospora ... -
Development and validation of a negative-strand-specific reverse transcription-PCR assay for detection of a chicken strain of hepatitis E virus: Identification of nonliver replication sites
(American Society for Microbiology, 2008-06-18)As a positive-strand RNA virus, hepatitis E virus ( HEV) produces an intermediate negative-strand RNA when it replicates. Thus, the detection of negative-strand viral RNA is indicative of HEV replication. The objective of ... -
Development of Sarcocystis falcatula in cell cultures demonstrates that it is different from Sarcocystis neurona
(Cambridge University Press, 1999-03)The development of Sarcocystis falcatula merozoites in bovine turbinate (BT) cell cultures is described and compared with development of Sarcocystis neurona merozoites. Merozoites of S. falcatula entered BT cell cultures ... -
Diagnostic accuracy of stereotactic brain biopsy for intracranial neoplasia in dogs: Comparison of biopsy, surgical resection, and necropsy specimens
(American College of Veterinary Internal Medicine, 2019-05)Background Stereotactic brain biopsy (SBB) is a technique that allows for definitive diagnosis of brain lesions. Little information is available regarding the diagnostic utility of SBB in dogs with intracranial diseases. ... -
Dielectrophoretic differentiation of mouse ovarian surface epithelial cells, macrophages, and fibroblasts using contactless dielectrophoresis
(American Institute of Physics, 2012-06-01)Ovarian cancer is the leading cause of death from gynecological malignancies in women. The primary challenge is the detection of the cancer at an early stage, since this drastically increases the survival rate. In this ... -
Dietary epicatechin improves survival and delays skeletal muscle degeneration in aged mice
(2019-01)We recently reported that epicatechin, a bioactive compound that occurs naturally in various common foods, promoted general health and survival of obese diabetic mice. It remains to be determined whether epicatechin extends ... -
Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury
(2019-06-12)The peripheral immune system is a major regulator of the pathophysiology associated with traumatic brain injury (TBI). While age-at-injury influences recovery from TBI, the differential effects on the peripheral immune ... -
Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury
(Springer Nature, 2019-06-12)The peripheral immune system is a major regulator of the pathophysiology associated with traumatic brain injury (TBI). While age-at-injury influences recovery from TBI, the differential effects on the peripheral immune ... -
Dopamine Stimulates Propagation of Toxoplasma gondii Tachyzoites in Human Fibroblast and Primary Neonatal Rat Astrocyte Cell Cultures
(American Society of Parasitology, 2012-12-01)Toxoplasma gondii is an obligate intracellular parasite often found in the brain of humans. Research has shown a correlation between prevalence of antibody titers to T. gondii and psychological illness in humans. Recent ... -
Effect of hydrogen peroxide and other protease inhibitors on Cryptosporidium parvum excystation and in vitro development
(American Society of Parasitology, 2004-08)This study was undertaken to observe the effects of hydrogen peroxide on Cryptosporidium parvum oocysts with respect to protease activity in comparison to known protease inhibitors. In assessing the possible mechanisms of ... -
Effect of Salmonella enterica serovar Typhimurium VNP20009 and VNP20009 with restored chemotaxis on 4T1 mouse mammary carcinoma progression
(Impact Journals Llc, 2017-05-16)A variety of bacterial strains have been evaluated as bio-therapeutic and immunomodulatory agents to treat cancer. One such strain, Salmonella enterica serovar Typhimurium VNP20009, which is attenuated by a purine auxotrophic ... -
Effects of Age and Breed on the Prevalence of Neospora caninum in Commercial Dairy Cattle from Pakistan
(American Society of Parasitology, 2013-04)Neospora caninum is a major cause of bovine abortion worldwide. A serological survey was carried out to determine the seroprevalence of exposure to N. caninum in dairy cattle based on age and breed from Punjab and Sindh ... -
Effects of Experimental Sarcocystis neurona-Induced Infection on Immunity in an Equine Model.
(2014)Sarcocystis neurona is the most common cause of Equine Protozoal Myeloencephalitis (EPM), affecting 0.5-1% horses in the United States during their lifetimes. The objective of this study was to evaluate the equine immune ... -
Effects of high pressure processing on infectivity of Toxoplasma gondii oocysts for mice
(American Society of Parasitology, 2005-06)High pressure processing (HPP) has been shown to be an effective non-thermal method of eliminating non-spore forming bacteria from a variety of food products. The shelf-life of the products is extended and the sensory ... -
Effects of high temperature and disinfectants on the viability of Sarcocystis neurona sporocysts
(American Society of Parasitology, 2002-12)The effect of moist heat and several disinfectants on Sarcocystis neurona sporocysts was investigated. Sporocysts (4 million) were suspended in water and heated to 50, 55, 60, 65, and 70 C for various times and were then ...
