Browsing Scholarly Works, Department of Biomedical Sciences and Pathobiology by Title
Now showing items 175-194 of 279
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Parenterally Administered P24-VP8* Nanoparticle Vaccine Conferred Strong Protection against Rotavirus Diarrhea and Virus Shedding in Gnotobiotic Pigs
(MDPI, 2019-11-06)Current live rotavirus vaccines are costly with increased risk of intussusception due to vaccine replication in the gut of vaccinated children. New vaccines with improved safety and cost-effectiveness are needed. In this ... -
The Parity-Associated Microenvironmental Niche in the Omental Fat Band Is Refractory to Ovarian Cancer Metastasis
(American Association for Cancer Research, 2013-09-10)Ovarian cancer is an insidious and aggressive disease of older women, typically undiscovered prior to peritoneal metastasis due to its asymptomatic nature and lack of early detection tools. Epidemiological studies suggest ... -
Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing
(2020-05-22)New methods of tumor ablation have shown exciting efficacy in pre-clinical models but often demonstrate limited success in the clinic. Due to a lack of quality or quantity in primary malignant tissue specimens, therapeutic ... -
Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage
(2019-11-11)Abstract Background The continuum of pro- and anti-inflammatory response elicited by traumatic brain injury (TBI) is suggested to play a key role in the outcome of TBI; however, ... -
Photonic Biosensor Assays to Detect and Distinguish Subspecies of Francisella tularensis
(MDPI, 2011-03-07)The application of photonic biosensor assays to diagnose the category-A select agent Francisella tularensis was investigated. Both interferometric and long period fiber grating sensing structures were successfully demonstrated; ... -
PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
(Cell Press, 2019-10-01)PINK1 and Parkin are established mediators of mitophagy, the selective removal of damaged mitochondria by autophagy. PINK1 and Parkin have been proposed to act as tumor suppressors, as loss-of-function mutations are ... -
Plexin-B2 and Plexin-D1 in Dendritic Cells: Expression and IL-12/IL-23p40 Production
(PLOS, 2012-08-15) -
Porcine enteritis associated with Eimeria spinosa Henry, 1931 infection
(American Society of Parasitology, 2002-12)Coccidia of the genus Eimeria arc present in roost pigs raised on dirt in the United States. They are generally considered nonpathogenic in weaned pigs. Oocysts of Eimeria spinoso Henry. 1931 were observed in tissue sections ... -
Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity
(Frontiers, 2017-05-09)N-methyl D-aspartate receptors (NMDAR) play crucial role in normal brain function and pathogenesis of neurodegenerative and psychiatric disorders. Functional tetra-heteromeric NMDAR contains two obligatory GluN1 subunits ... -
Potential mechanisms of attenuation for rifampicin-passaged strains of Flavobacterium psychrophilum
(Biomed Central Ltd, 2015-09-16)Background Flavobacterium psychrophilum is the etiologic agent of bacterial coldwater disease in salmonids. Earlier research showed that a rifampicin-passaged strain of F. psychrophilum (CSF 259-93B.17) caused no disease ... -
Potential of Stem Cell-Based Therapy for Ischemic Stroke
(Frontiers, 2018-02-06)Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several studies have been devoted to assessing the ... -
Pregnancy and lactation interfere with the response of autoimmunity to modulation of gut microbiota
(2019-07-16)Abstract Background Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). Lupus patients who ... -
Prevalence of agglutinating antibodies to Neospora caninum in raccoons, Procyon lotor
(American Society of Parasitology, 2001-10)Neospora caninum is an apicomplexan parasite that causes neonatal neuromuscular disease in dogs and abortions in cattle. Dogs are the only proven definitive host. Little is known about the prevalence of antibodies to this ... -
Prevalence of agglutinating antibodies to Sarcocystis neurona in raccoons (Procyon lotor) from an urban area of Virginia
(American Society of Parasitology, 2004-08)Equine protozoal myeloencephalitis is the most important protozoan disease of horses in North America and is usually caused by Sarcocystis neurona. Natural and experimentally induced cases of encephalitis caused by S. ... -
Prevalence of agglutinating antibodies to Sarcocystis neurona in skunks (Mephitis mephitis), raccoons (Procyon lotor), and opossums (Didelphis virginiana) from Connecticut
(American Society of Parasitology, 2002-10)Equine protozoal myeloencephalitis is the most important protozoan disc a 6 of horses in North America and is usually caused by Sarcocystis neuronal Natural cases of encephalitis caused by S. neurona have been reported in ... -
Prevalence of agglutinating antibodies to Toxoplasma gondii and Sarcocystis neurona in beavers (Castor canadensis) from Massachusetts
(American Society of Parasitology, 2005-10)The present study examined the seroprevalence of Toxoplasma gondii and Sarcocystis neurona in a population of beavers (Castor canadensis) from Massachusetts. Sixty-two blood samples were collected during the field seasons ... -
Prevalence of agglutinating antibodies to Toxoplasma gondii in adult and fetal mule deer (Odocoileus hemionus) from Nebraska
(American Society of Parasitology, 2005-12)Toxoplasma gondii is an apicomplexan parasite of mammals and birds. Herbivores acquire postnatal infection by ingesting oocysts from contaminated food or water. Toxoplasma gondii infection is common in white-tailed deer, ... -
Prevalence of agglutinating antibodies to Toxoplasma gondii in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from Connecticut
(American Society of Parasitology, 2006-06)The prevalence of agglutinating antibodies to Toxoplasma gondii was examined in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from 8 cities in Connecticut. Ten (42%) of ... -
Prevalence of antibodies to Leishmania infantum and Trypanosoma cruzi in wild canids from South Carolina
(American Society of Parasitology, 2007-08)Wild canids are reservoir hosts for Leishmania infantum and Trypanosoma cruzi.. The present study examined the prevalence of antibodies to these zoonotic parasites in a population of wild canids from a nonagricultural ... -
Prevalence of antibodies to Neospora caninum and Sarcocystis neurona in sera of domestic cats from Brazil
(American Society of Parasitology, 2002-12)Antibodies to Neospora caninum and Sarcocystis neurona were determined in serum samples of 502 domestic cats from Brazil using direct agglutination tests with the respective antigens. Antibodies to S. neurona were not found ...
