Browsing Scholarly Works, Department of Biomedical Sciences and Pathobiology by Title
Now showing items 209-228 of 267
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Rapid virulence prediction and identification of Newcastle disease virus genotypes using third-generation sequencing
(2018-11-22)Abstract Background Newcastle disease (ND) outbreaks are global challenges to the poultry industry. Effective management requires rapid identification and virulence prediction ... -
Re-Evaluation of Asynchronous Asexual Development of Cystoisospora canis in Intestines of Dogs
(2019-01-28)The coccidian parasite Cystoisospora canis (syn. Isospora canis) can cause clinical disease in dogs. Three generation of schizonts have been reported in the small intestine of dogs before oocysts are excreted 9-11 days ... -
Real-time prediction of patient immune cell modulation during irreversible electroporation therapy
(2019-11-28)Immunotherapies have demonstrated limited efficacy in pancreatic ductal adenocarcinoma (PDAC) patients despite their success in treating other tumor types. This limitation is largely due to the relatively immunosuppressive ... -
Recent advances in Brucella abortus vaccines
(2015-07-08)Brucella abortus vaccines play a central role in bovine brucellosis control/eradication programs and have been successfully used worldwide for decades. Strain 19 and RB51 are the approved B. abortus vaccines strains most ... -
Regulation of Cytoskeleton Organization by Sphingosine in a Mouse Cell Model of Progressive Ovarian Cancer
(MDPI, 2013-07-16)Ovarian cancer is a multigenic disease and molecular events driving ovarian cancer progression are not well established. We have previously reported the dysregulation of the cytoskeleton during ovarian cancer progression ... -
Regulation of IL-17 in autoimmune diseases by transcriptional factors and microRNAs
(Frontiers, 2015-07-14)In recent years, IL-17A (IL-17), a pro-inflammatory cytokine, has received intense attention of researchers and clinicians alike with documented effects in inflammation and autoimmune diseases. IL-17 mobilizes, recruits ... -
Regulatory T Cells in Arterivirus and Coronavirus Infections: Do They Protect Against Disease or Enhance it?
(MDPI, 2012-05-01)Regulatory T cells (Tregs) are a subset of T cells that are responsible for maintaining peripheral immune tolerance and homeostasis. The hallmark of Tregs is the expression of the forkhead box P3 ... -
Restricted Enzooticity of Hepatitis E Virus Genotypes 1 to 4 in the United States
(American Society for Microbiology, 2011-10-12)Hepatitis E is recognized as a zoonosis, and swine are known reservoirs, but how broadly enzootic its causative agent, hepatitis E virus (HEV), is remains controversial. To determine the prevalence of HEV infection in ... -
Retinal-input-induced epigenetic dynamics in the developing mouse dorsal lateral geniculate nucleus
(2019-02-14)Abstract DNA methylation plays important roles in the regulation of nervous system development and in cellular responses to environmental stimuli such as light-derived signals. Despite great efforts in ... -
Retinoic Acid, Leaky Gut, and Autoimmune Diseases
(MDPI, 2018-08-03)A leaky gut has been observed in a number of autoimmune diseases including type 1 diabetes, multiple sclerosis, inflammatory bowel disease, and systemic lupus erythematosus. Previous studies from our laboratory have shown ... -
Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells
(PLoS One, 2015-12-08)Background Recent clinical trials using c-kit+ human cardiac stem cells (CSCs) demonstrated promising results in increasing cardiac function and improving quality of life. However, CSC efficiency is low, likely due to ... -
Rice Bran and Probiotics Alter the Porcine Large Intestine and Serum Metabolomes for Protection against Human Rotavirus Diarrhea
(Frontiers, 2017-04-21)Human rotavirus (HRV) is a leading cause of severe childhood diarrhea, and there is limited vaccine efficacy in the developing world. Neonatal gnotobiotic pigs consuming a prophylactic synbiotic combination of probiotics ... -
Rice bran supplementation modulates growth, microbiota and metabolome in weaning infants: a clinical trial in Nicaragua and Mali
(Springer Nature, 2019-09-26)Rice bran supplementation provides nutrients, prebiotics and phytochemicals that enhance gut immunity, reduce enteric pathogens and diarrhea, and warrants attention for improvement of environmental enteric dysfunction (EED) ... -
Risk factors associated with exposure to bovine respiratory disease pathogens during the peri-weaning period in dairy bull calves
(2018-02-27)Abstract Background Bovine respiratory disease (BRD) remains among the leading causes of death of cattle internationally. The objective of this study was to identify risk ... -
Role of Lactobacillus reuteri in Human Health and Diseases
(Frontiers, 2018-04-19)Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a large number of mammals. In humans, L. reuteri is found in different body sites, including the gastrointestinal tract, urinary ... -
Safety and Immunogenicity of a Mycoplasma ovipneumoniae bacterin for domestic sheep (Ovis aries).
(2014)BACKGROUND: Mortality from epizootic pneumonia is hindering re-establishment of bighorn sheep populations in western North America. Mycoplasma ovipneumoniae, a primary agent of this disease, is frequently carried ... -
Sarcocystis campestris from naturally infected 13-lined ground squirrels, Spermophilus tridecemlineatus tridecemlineatus, from Nebraska
(American Society of Parasitology, 2000-10)Grossly visible sarcocysts were seen in the skeletal muscles of 1 of 12 13-lined ground squirrels, Spermophilus tridecemlineatus tridecemlineatus, collected in Nebraska. The tissue cyst wall was up to 5.0 mum thick and ... -
Sarcocystis Jamaicensis N. Sp., From Red-Tailed Hawks (Buteo Jamaicensis) Definitive Host and Ifn-Gamma Gene Knockout Mice as Experimental Intermediate Host
(2017-10)Here, we report a new species of Sarcocystis with red-tailed hawk (RTH, Buteo jamaicensis) as the natural definitive host and IFN-gamma gene knockout (KO) mice as an experimental intermediate host in which sarcocysts form ...
