Browsing Scholarly Works, Department of Biomedical Sciences and Pathobiology by Title
Now showing items 271-279 of 279
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The U-Rich Untranslated Region of the Hepatitis E Virus Induces Differential Type I and Type III Interferon Responses in a Host Cell-Dependent Manner
(2020-01-14)Hepatitis E virus (HEV), a single-strand positive-sense RNA virus, is an understudied but important human pathogen. The virus can establish infection at a number of host tissues, including the small intestine and liver, ... -
The Upregulation of Genomic Imprinted DLK1-Dio3 miRNAs in Murine Lupus Is Associated with Global DNA Hypomethylation
(PLOS, 2016-04-12)Epigenetic factors such as DNA methylation and microRNAs (miRNAs) are now increasingly recognized as vital contributors to lupus etiology. In this study, we investigated the potential interaction of these two epigenetic ... -
Use of molecular probes to assess geographic distribution of Pfiesteria species
(US Department of Health and Human Sciences, Public Health Science, 2001-10-01)We have developed multiple polymerase chain reaction (PCR)-based methods for the detection of Pfiesteria sp. in cultures and environmental samples. More than 2,100 water and sediment samples from estuarine sites of the ... -
Vaccination of Elk (Cervus canadensis) with Brucella abortus Strain RB51 Overexpressing Superoxide Dismutase and Glycosyltransferase Genes Does Not Induce Adequate Protection against Experimental Brucella abortus Challenge
(Frontiers, 2016-02-10)In recent years, elk (Cervus canadensis) have been implicated as the source of Brucella abortus infection for numerous cattle herds in the Greater Yellowstone Area. In the face of environmental and ecological changes on ... -
Vaccination of mice with Neospora caninum: Response to oral challenge with Toxoplasma gondii oocysts
(American Society of Parasitology, 1998-04)Neospora caninum is a protozoan parasite that can cause severe disease in mammals. Two experiments were conducted to examine the effects of subcutaneous (s.c.) vaccination with Hank's balanced salt solution (HBSS), 1 x ... -
Variation in Eimeria oocyst count and species composition in weanling beef heifers
(American Society of Parasitology, 2006-10)Rectal fecal samples were collected daily on 10 consecutive days in November 2004 from I I weaned beef heifers to assess daily variation in fecal oocyst count and species composition. Subsequent samples were collected from ... -
Virtual methylome dissection facilitated by single-cell analyses
(2019-11-11)Abstract Background Numerous cell types can be identified within plant tissues and animal organs, and the epigenetic modifications underlying such enormous cellular heterogeneity are just beginning to be understood. It ... -
Whole Brain Radiation-Induced Impairments in Learning and Memory Are Time-Sensitive and Reversible by Systemic Hypoxia
(PLOS, 2012-01-18)Whole brain radiation therapy (WBRT) is commonly used for treatment of primary and metastatic brain tumors; however, cognitive impairment occurs in 40–50% of brain tumor survivors. The etiology of the cognitive impairment ... -
Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
(2020-06)Author summary Animals develop from a single cell to form a complex organism with many specialised cells. Almost all of the fantastic variety of cells must have the same sequence of DNA, and yet they have distinct identities ...
