Now showing items 93-112 of 276

    • The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers 

      Ginja, Catarina; Gama, Luis Telo; Cortes, Oscar; Martin Burriel, Inmaculada; Luis Vega-Pla, Jose; Penedo, Cecilia; Sponenberg, Phil; Canon, Javier; Sanz, Arianne; do Egito, Andrea Alves; Angela Alvarez, Luz; Giovambattista, Guillermo; Agha, Saif; Rogberg-Munoz, Andres; Cassiano Lara, Maria Aparecida; Vicente Delgado, Juan; Martinez, Amparo; Afonso, Sonia; Aguirre, Lenin; Armstrong, Eileen; Camacho Vallejo, Maria Esperanza; Canales, Amado; Cassama, Bernardo; Contreras, Gloria; Moras Cordeiro, J. M.; Dunner, Susana; Elbeltagy, Ahmed; Soares Fioravanti, Maria Clorinda; Gomez Carpio, Mayra; Gomez, Mariano; Hernandez, Antonio; Hernandez, Darwin; Juliano, Raquel Soares; Landi, Vincenzo; Marques, Ribamar; Martinez, Ruben D.; Roberto Martinez, O.; Melucci, Lilia; Molina Flores, Baldomero; Mujica, Fernando; Pares i Casanova, Pere-Miquel; Quiroz, Jorge; Rodellar, Clementina; Tjon, Gerald; Adebambo, Tumininu; Uffo, Odalys; Cesar Vargas, Julio; Villalobos, Axel; Zaragoza, Pilar (Springer Nature, 2019-08-07)
      Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received influences ...
    • Genetic determinants restricting the reassortment of heterologous NSP2 genes into the simian rotavirus SA11 genome 

      Mingo, Rebecca; Zhang, Shu; Long, Courtney P.; LaConte, Leslie E. W.; McDonald, Sarah M. (Springer Nature, 2017-08-24)
      Rotaviruses (RVs) can evolve through the process of reassortment, whereby the 11 double-stranded RNA genome segments are exchanged among strains during co-infection. However, reassortment is limited in cases where the genes ...
    • Genotypic and Pathotypic Characterization of Newcastle Disease Viruses from India 

      Tirumurugaan, Krishnaswamy G.; Kapgate, Sunil; Vinupriya, Manavalan K.; Vijayarani, Kumanan; Kumanan, Kathaperumal; Elankumaran, Subbiah (PLOS, 2011-12-09)
      Newcastle disease virus (NDV) is an avian paramyxovirus that causes significant economic losses to the poultry industry in most parts of the world. The susceptibility of a wide variety of avian species coupled with ...
    • Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice 

      Catanzaro, Kelly C. Freudenberger; Champion, Anna E.; Mohapatra, Nrusingh; Cecere, Thomas E.; Inzana, Thomas J. (Frontiers, 2017-05-30)
      Francisella tularensis is a Gram-negative bacterium and the etiologic agent of tularemia. F. tularensis may appear encapsulated when examined by transmission electron microscopy (TEM), which is due to production of an ...
    • Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1 

      TeKippe, EM; Allen, IC; Hulseberg, PD; Sullivan, Jonathan T.; McCann, JR; Sandor, M; Braunstein, M; Ting, JP-Y (PLOS, 2010-08-20)
    • Heartland Virus Epidemiology, Vector Association, and Disease Potential 

      Brault, Aaron C.; Savage, Harry M.; Duggal, Nisha K.; Eisen, Rebecca J.; Staples, J. Erin (MDPI, 2018-09-14)
      First identified in two Missouri farmers exhibiting low white-blood-cell and platelet counts in 2009, Heartland virus (HRTV) is genetically closely related to severe fever with thrombocytopenia syndrome virus (SFTSV), a ...
    • Hepatitis E Virus in Pigs from Slaughterhouses, United States, 2017-2019 

      Sooryanarain, Harini; Heffron, Connie L.; Hill, Dolores E.; Fredericks, Jorrell; Rosenthal, Benjamin M.; Werre, Stephen R.; Opriessnig, Tanja; Meng, Xiang-Jin (2020-02)
      Hepatitis E virus (HEV) RNA was detected in 6.3% and HEV IgG in 40% of 5,033 serum samples from market-weight pigs at 25 slaughterhouses in 10 US states. The prevalent HEV genotype was zoonotic genotype 3, group 2. Blood ...
    • Hepatitis E Virus in Rabbits, Virginia, USA 

      Cossaboom, Caitlin M.; Cordoba, Laura; Dryman, Barbara A.; Meng, Xiang-Jin (2011-11)
      We identified hepatitis E virus (HEV) in rabbits in Virginia, USA. HEV RNA was detected in 14 (16%) of 85 serum samples and 13 (15%) of 85 fecal samples. Antibodies against HEV were detected in 31 (36%) of 85 serum samples. ...
    • Hepatitis E Virus Seroprevalence and Associated Risk Factors in Apparently Healthy Individuals from Osun State, Nigeria 

      Osundare, Folakemi Abiodun; Klink, Patrycja; Majer, Catharina; Akanbi, Olusola Aanuoluwapo; Wang, Bo; Faber, Mirko; Harms, Dominik; Bock, C.-Thomas; Opaleye, Oladele Oluyinka (MDPI, 2020-05-20)
      Hepatitis E virus (HEV) infection is a major public health concern in low-income countries, yet incidence and prevalence estimates are often lacking. Serum (n = 653) and faecal (n = 150) samples were collected ...
    • Herpes Simplex Virus 1 Reactivates from Autonomic Ciliary Ganglia Independently from Sensory Trigeminal Ganglia To Cause Recurrent Ocular Disease 

      Lee, Sungseok; Ives, Angela M.; Bertke, Andrea S. (American Society for Microbiology, 2015-08-01)
      Herpes simplex virus 1 (HSV-1) and HSV-2 establish latency in sensory and autonomic neurons after ocular or genital infection, but their recurrence patterns differ. HSV-1 reactivates from latency to cause recurrent orofacial ...
    • High Protective Efficacy of Probiotics and Rice Bran against Human Norovirus Infection and Diarrhea in Gnotobiotic Pigs 

      Lei, Shaohua; Ramesh, Ashwin; Twitchell, Erica; Wen, Ke; Bui, Tammy; Weiss, Mariah; Yang, Xingdong; Kocher, Jacob; Li, Guohua; Giri-Rachman, Ernawati; Trang, Nguyen Van; Jiang, Xi; Ryan, Elizabeth P.; Yuan, Lijuan (2016)
      Probiotics have been recognized as vaccine adjuvants and therapeutic agents to treat acute gastroenteritis in children. We previously showed that rice bran (RB) reduced human rotavirus diarrhea in gnotobiotic pigs. Human ...
    • High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity 

      Yang, Xingdong; Twitchell, Erica; Li, Guohua; Wen, Ke; Weiss, Mariah; Kocher, Jacob; Lei, Shaohua; Ramesh, Ashwin; Ryan, Elizabeth P.; Yuan, Lijuan (Nature Publishing Group, 2015-10-13)
      Previously, we showed that rice bran (RB) was able to reduce human rotavirus (HRV) diarrhea in gnotobiotic pigs. Here, we investigated its effect on the growth of diarrhea-reducing probiotic Lactobacillus rhamnosus GG (LGG) ...
    • High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity 

      Ringel-Scaia, Veronica M.; Beitel-White, Natalie; Lorenzo, Melvin F.; Brock, Rebecca M.; Huie, Kathleen E.; Coutermarsh-Ott, Sheryl; Eden, Kristin; McDaniel, Dylan K.; Verbridge, Scott; Rossmeisl, John H., Jr.; Oestreich, Kenneth J.; Davalos, Rafael, V; Allen, Irving C. (2019-06)
      Background: Despite promising treatments for breast cancer, mortality rates remain high and treatments for metastatic disease are limited. High-frequency irreversible electroporation (H-FIRE) is a novel tumor ablation ...
    • Histopathologic Variation between Liver Lobes in Dogs 

      Kemp, S. D.; Zimmerman, K. L.; Panciera, D. L.; Monroe, W. E.; Leib, M. S. (American College of Veterinary Internal Medicine, 2015-01)
      Background: Biopsy of the liver evaluates a small portion of tissue, with inferences made to the entire organ. The method and number of biopsies obtained are tempered by consideration of the risks and benefits. Recommendations ...
    • Horses experimentally infected with sarcocystis neurona develop altered immune responses in vitro 

      Witonsky, Sharon G.; Ellison, Siobhan; Yang, Jibing; Gogal, Robert M.; Lawler, Heather; Suzuki, Yasuhiro; Sriranganathan, Namalwar; Andrews, Frank; Ward, Daniel; Lindsay, David S. (American Society of Parasitology, 2008-10)
      Equine protozoal myeloencephalitis (EPM) due to Sarcocystis neurona infection is I of the most common neurologic diseases in horses in the United States. The mechanisms by which most horses resist disease, as well as the ...
    • Host nutritional status affects alphavirus virulence, transmission, and evolution 

      Weger-Lucarelli, James; Carrau, Lucia; Levi, Laura I.; Rezelj, Veronica; Vallet, Thomas; Blanc, Herve; Boussier, Jeremy; Megrian, Daniela; Coutermarsh-Ott, Sheryl; LeRoith, Tanya; Vignuzzi, Marco (2019-11)
      Malnourishment, specifically overweight/obesity and undernourishment, affects more than 2.5 billion people worldwide, with the number affected ever-increasing. Concurrently, emerging viral diseases, particularly those that ...
    • Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis 

      Zhang, Zhenlu; He, Guijuan; Han, Gil-Soo; Zhang, Jiantao; Catanzaro, Nicholas; Diaz, Arturo; Wu, Zujian; Carman, George M.; Xie, Lianhui; Wang, Xiaofeng (PLOS, 2018-04-12)
      Replication of positive-strand RNA viruses [(+)RNA viruses] takes place in membrane-bound viral replication complexes (VRCs). Formation of VRCs requires virus-mediated manipulation of cellular lipid synthesis. Here, we ...
    • ICTV Virus Taxonomy Profile: Hepeviridae 

      Purdy, Michael A.; Harrison, Tim J.; Jameel, S.; Meng, Xiang-Jin; Okamoto, H.; Van der Poel, W. H. M.; Smith, Donald B. (2017-11)
      The family Hepeviridae includes enterically transmitted small non-enveloped positive-sense RNA viruses. It includes the genera Piscihepevirus, whose members infect fish, and Orthohepevirus, whose members infect mammals and ...
    • Identification and Fine Mapping of Nuclear and Nucleolar Localization Signals within the Human Ribosomal Protein S17 

      Kenney, Scott P.; Meng, Xiang-Jin (PLOS, 2015-04-08)
      Human ribosomal protein S17 (RPS17) is mutated in Diamond-Blackfan Anemia (DBA), a bone marrow disorder that fails to produce sufficient red blood cells leading to anemia. Recently, an RPS17 protein sequence was also found ...
    • Identification of a Common Lupus Disease-Associated microRNA Expression Pattern in Three Different Murine Models of Lupus 

      Dai, Rujuan; Zhang, Yan; Khan, Deena; Heid, Bettina; Caudell, David; Crasta, Oswald; Ahmed, S. Ansar (PLOS, 2010-12-10)
      Background Recent reports have shown that microRNAs (miRNAs) regulate vital immunological processes and have emerged as key regulators of immune system development and function. Therefore, it is important to determine ...