Now showing items 16-34 of 34

    • Herpes Simplex Virus 1 Reactivates from Autonomic Ciliary Ganglia Independently from Sensory Trigeminal Ganglia To Cause Recurrent Ocular Disease 

      Lee, Sungseok; Ives, Angela M.; Bertke, Andrea S. (American Society for Microbiology, 2015-08-01)
      Herpes simplex virus 1 (HSV-1) and HSV-2 establish latency in sensory and autonomic neurons after ocular or genital infection, but their recurrence patterns differ. HSV-1 reactivates from latency to cause recurrent orofacial ...
    • LAT Region Factors Mediating Differential Neuronal Tropism of HSV-1 and HSV-2 Do Not Act in Trans 

      Bertke, Andrea S.; Apakupakul, K.; Ma, AyeAye; Imai, Y; Gussow, AM; Wang, K; Cohen, JI; Bloom, DC; Margolis, Todd P. (PLOS, 2012-12-31)
      After HSV infection, some trigeminal ganglion neurons support productive cycle gene expression, while in other neurons the virus establishes a latent infection. We previously demonstrated that HSV-1 and HSV-2 preferentially ...
    • Lost in translation: Delivering culturally and linguistically appropriate interventions to Hispanic populations 

      Valenzuela, Ivette (2015)
      Hispanics became the United States' largest minority in 2012. Lack of culturally and linguistically appropriate interventions in the Hispanic population at the health-care and community levels increases the risk of negative ...
    • A Mathematical Model of Skeletal Muscle Disease and Immune Response in the mdx Mouse 

      Jarrah, Abdul Salam; Castiglione, Filippo; Evans, Nicholas P.; Grange, Robert W.; Laubenbacher, Reinhard (Hindawi, 2014-06-11)
      Duchenne muscular dystrophy (DMD) is a genetic disease that results in the death of affected boys by early adulthood. The genetic defect responsible for DMD has been known for over 25 years, yet at present there is neither ...
    • Modeling the burden of poultry disease on the rural poor in Madagascar 

      Rist, Cassidy; Ngonghala, Calistus N.; Garchitorena, Andres; Brook, Cara E.; Ramananjato, Ranto; Miller, Ann C.; Randrianarivelojosia, Milijaona; Wright, Patricia C.; Gillespie, Thomas R.; Bonds, Matthew H. (2015-12)
    • Multi-scale immunoepidemiological modeling of within-host and between-host HIV dynamics: systematic review of mathematical models 

      Dorratoltaj, Nargesalsadat; Nikin-Beers, Ryan; Ciupe, Stanca M.; Eubank, Stephen G.; Abbas, Kaja M. (PeerJ, 2017-09-28)
      Objective The objective of this study is to conduct a systematic review of multi-scale HIV immunoepidemiological models to improve our understanding of the synergistic impact between the HIV viral-immune dynamics at the ...
    • Navigable rivers facilitated the spread and recurrence of plague in pre-industrial Europe 

      Yue, Ricci P. H.; Lee, Harry F.; Wu, Connor Y. H. (Springer Nature, 2016-10-10)
      Infectious diseases have become a rising challenge to mankind in a globalizing world. Yet, little is known about the inland transmission of infectious diseases in history. In this study, we based on the spatiotemporal ...
    • Neurotrophic Factors NGF, GDNF and NTN Selectively Modulate HSV1 and HSV2 Lytic Infection and Reactivation in Primary Adult Sensory and Autonomic Neurons 

      Yanez, Andy A.; Harrell, Telvin; Sriranganathan, Heather J.; Ives, Angela M.; Bertke, Andrea S. (MDPI, 2017-02-07)
      Herpes simplex viruses (HSV1 and HSV2) establish latency in peripheral ganglia after ocular or genital infection, and can reactivate to produce different patterns and frequencies of recurrent disease. Previous studies ...
    • A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications 

      Guo, Sujuan; Liang, Yanping; Murphy, Susan F.; Huang, Angela; Shen, Haihong; Kelly, Deborah F.; Sobrado, Pabla; Sheng, Zhi (Taylor & Francis Inc, 2015-03-01)
    • Rethinking health systems strengthening: key systems thinking tools and strategies for transformational change 

      Swanson, RC; Cattaneo, A; Bradley, E; Chunharas, S; Atun, R; Abbas, KM; Katsaliaki, K; Mustafee, N; Mason Meier, B; Best, A (Oxford Univ Press, 2012-10-01)
    • Role of bacille Calmette-Guérin in preventing tuberculous infection. 

      Adinarayanan, S; Culp, RK; Subramani, R; Abbas, KM; Radhakrishna, S; Swaminathan, S (2017-04-01)
      SETTING: Rural community in South India. OBJECTIVE: To determine the role of bacille Calmette-Guérin (BCG) in preventing tuberculous infection in children. DESIGN: A prevalence survey was undertaken in 1999-2001 in a ...
    • Spatial Big Data Analytics of Influenza Epidemic in Vellore, India 

      Lopez, D; Gunasekaran, M; Murugan, BS; Kaur, H; Abbas, KM (IEEE, 2014-01-01)
    • Studies in Big Data Series: Internet of Things and Big Data Technologies for Next Generation Healthcare 

      Abbas, KM; Manogaran, G; Thota, C; Lopez, D; Vijayakumar, V; Sundarsekar, R (2017)
    • Temperature and heat in informal settlements in Nairobi 

      Scott, Anna A.; Misiani, Herbert; Okoth, Terrify; Jordan, Asha; Gohlke, Julia; Ouma, Gilbert; Arrighi, Julie; Zaitchik, Ben F.; Jjemba, Eddie; Verjee, Safia; Waugh, Darryn W. (PLOS, 2017-11-06)
      Nairobi, Kenya exhibits a wide variety of micro-climates and heterogeneous surfaces. Paved roads and high-rise buildings interspersed with low vegetation typify the central business district, while large neighborhoods of ...
    • Trade routes and plague transmission in pre-industrial Europe 

      Yue, Ricci P. H.; Lee, Harry F.; Wu, Connor Y. H. (Springer Nature, 2017-10-11)
      Numerous historical works have mentioned that trade routes were to blame for the spread of plague in European history, yet this relationship has never been tested by quantitative evidence. Here, we resolve the hypothetical ...
    • Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990-2015: findings from the Global Burden of Disease 2015 study 

      Mokdad, Ali H.; El Bcheraoui, Charbel; Wang, Haidong; Charara, Raghid; Khalil, Ibrahim; Moradi-Lakeh, Maziar; Afshin, Ashkan; Collison, Michael; Daoud, Farah; Chew, Adrienne; Krohn, Kristopher J.; Carter, Austin; Foreman, Kyle J.; He, Fei; Kassebaum, Nicholas J.; Kutz, Michael; Mirarefin, Mojde; Nguyen, Grant; Silpakit, Naris; Sligar, Amber; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw Ferede; Adane, Kelemework; Agarwal, Arnav; Kiadaliri, Aliasghar Ahmad; Ahmadi, Alireza; Ahmed, Muktar Beshir; Al Lami, Faris Hasan; Alam, Khurshid; Alasfoor, Deena; Alizadeh-Navaei, Reza; Al-Maskari, Fatma; Al-Raddadi, Rajaa; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Ammar, Walid; Anber, Nahla; Antonio, Carl Abelardo T.; Anwari, Palwasha; Asayesh, Hamid; Asghar, Rana Jawad; Atey, Tesfay Mehari; Avokpaho, Euripide Frinel G. Arthur; Ayele, Tadesse Awoke; Azzopardi, Peter; Bacha, Umar; Barac, Aleksandra; Baernighausen, Till; Bazargan-Hejazi, Shahrzad; Geffen, David; Bedi, Neeraj; Bensenor, Isabela M.; Berhane, Adugnaw; Bessong, Pascal Obong; Beyene, Addisu Shunu; Bhutta, Zulfiqar A.; Birungi, Charles; Butt, Zahid A.; Cahuana-Hurtado, Lucero; Danawi, Hadi; das Neves, Jose; Deribe, Kebede; Deribew, Amare; Jarlais, Don C. Des; Dharmaratne, Samath D.; Djalalinia, Shirin; Doyle, Kerrie E.; Endries, Aman Yesuf; Eshrati, Babak; Faraon, Emerito Jose Aquino; Farvid, Maryam S.; Fereshtehnejad, Seyed-Mohammad; Feyissa, Tesfaye Regassa; Fischer, Florian; Garcia-Basteiro, Alberto L.; Gebrehiwot, Tsegaye Tewelde; Gesesew, Hailay Abrha; Gishu, Melkamu Dedefo; Glaser, Elizabeth; Gona, Philimon N.; Gugnani, Harish Chander; Gupta, Rahul; Bidgoli, Hassan Haghparast; Hailu, Gessessew Bugssa; Hamadeh, Randah Ribhi; Hambisa, Mitiku Teshome; Hamidi, Samer; Harb, Hilda L.; Hareri, Habtamu Abera; Horita, Nobuyuki; Husseini, Abdullatif; Ibrahim, Ahmed; James, Spencer Lewis; Jonas, Jost B.; Kasaeian, Amir; Kassaw, Nigussie Assefa; Khader, Yousef Saleh; Khan, Ejaz Ahmad; Khan, Gulfaraz; Khoja, Abdullah Tawfih Abdullah; Khubchandani, Jagdish; Kim, Yun Jin; Koyanagi, Ai; Defo, Barthelemy Kuate; Larson, Heidi J.; Latif, Asma Abdul; Leshargie, Cheru Tesema; Lunevicius, Raimundas; Abd El Razek, Mohammed Magdy; Majdzadeh, Reza; Majeed, Azeem; Malekzadeh, Reza; Manyazewal, Tsegahun; Markos, Desalegn; Farid, Habibolah Masoudi; Mehari, Alem; Mekonnen, Alemayehu B.; Memiah, Peter; Memish, Ziad A.; Mendoza, Walter; Mengesha, Melkamu Merid; Mengistu, Desalegn Tadese; Mezgebe, Haftay Berhane; Mhimbira, Francis Apolinary; Miller, Ted R.; Moore, Ami R.; Mumtaz, Ghina R.; Natarajan, Gopalakrishnan; Negin, Joel; Obermeyer, Carla Makhlouf; Ogbo, Felix Akpojene; Oh, In-Hwan; Ota, Erika; Pereira, David M.; Pourmalek, Farshad; Qorbani, Mostafa; Radfar, Amir; Rafay, Anwar; Rahimi-Movaghar, Vafa; Rai, Rajesh Kumar; Ram, Usha; Rawaf, David Laith; Rawaf, Salman; Renzaho, Andre M. N.; Rezaei, Satar; Rezai, Mohammad Sadegh; Roba, Hirbo Shore; Roshandel, Gholamreza; Safdarian, Mahdi; Safiri, Saeid; Sahraian, Mohammad Ali; Salamati, Payman; Samy, Abdallah M.; Sartorius, Benn; Sepanlou, Sadaf G.; Shaikh, Masood Ali; Shamsizadeh, Morteza; Sibamo, Ephrem Lejore Sibamo; Singh, Jasvinder A.; Sobaih, Badr H. A.; Soshnikov, Sergey; Sufiyan, Muawiyyah Babale; Sykes, Bryan L.; Taveira, Nuno; Tegegne, Teketo Kassaw; Tehrani-Banihashemi, Arash; Tekelab, Tesfalidet; Shifa, Girma Temam; Temsah, Mohamad-Hani; Tesssema, Belay; Topor-Madry, Roman; Ukwaja, Kingsley Nnanna; Uthman, Olalekan A.; Vollset, Stein Emil; Wadilo, Fiseha; Wakayo, Tolassa; Alebachew, Minyahil; Workicho, Abdulhalik; Workie, Shimelash Bitew; Yaghoubi, Mohsen; Yalew, Ayalnesh Zemene; Yimam, Hassen Hamid; Yonemoto, Naohiro; Yoon, Seok-Jun; Yotebieng, Marcel; Younis, Mustafa Z.; Zaki, Maysaa El Sayed; Jumaan, Aisha O.; Vos, Theo; Hay, Simon I.; Naghavi, Mohsen; Murray, Christopher J. L. (2018-05)
      We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Tailored estimation methods were used to produce ...
    • A VP26-mNeonGreen Capsid Fusion HSV-2 Mutant Reactivates from Viral Latency in the Guinea Pig Genital Model with Normal Kinetics 

      Pieknik, JR; Bertke, Andrea S.; Tang, S; Krause, PR (MDPI, 2018-05-01)
      Fluorescent herpes simplex viruses (HSV) are invaluable tools for localizing virus in cells, permitting visualization of capsid trafficking and enhancing neuroanatomical research. Fluorescent viruses can also be used to ...
    • Zika Virus Persistently and Productively Infects Primary Adult Sensory Neurons In Vitro 

      Swartwout, Brianna K.; Zlotnick, Marta G.; Saver, Ashley E.; McKenna, Caroline M.; Bertke, Andrea S. (MDPI, 2017-10-13)
      Zika virus (ZIKV) has recently surged in human populations, causing an increase in congenital and Guillain-Barré syndromes. While sexual transmission and presence of ZIKV in urine, semen, vaginal secretions, and saliva ...