Browsing Scholarly Works, Small Animal Clinical Sciences by Issue Date

Transplacental transmission of a North American isolate of Leishmania infantum in an experimentally infected beagle

Rosypal, A. C.; Troy, Gregory C.; Zajac, Anne M.; Frank, G.; Lindsay, David S. (American Society of Parasitology, 2005-08)

Leishmania infantum, an etiologic agent of zoonotic visceral leishmaniasis, is widespread among foxhounds in the United States. Although sand flies are widely distributed throughout the United States, epidemiological data ...

Effects of descending positive end-expiratory pressure on lung mechanics and aeration in healthy anaesthetized piglets.

Carvalho, A. R.; Jandre, F. C.; Pino, A. V.; Bozza, F. A.; Salluh, J. I.; Rodrigues, R.; Soares, J. H.; Giannella-Neto, A. (2006)

INTRODUCTION: Atelectasis and distal airway closure are common clinical entities of general anaesthesia. These two phenomena are expected to reduce the ventilation of dependent lung regions and represent major causes of ...

Efficacy of temozolomide or dacarbazine in combination with an anthracycline for rescue chemotherapy in dogs with lymphoma

Dervisis, Nikolaos G.; Dominguez, Pedro A.; Sarbu, Luminita; Newman, Rebecca G.; Cadile, Casey D.; Swanson, Christine N.; Kitchell, Barbara E. (Amer Veterinary Medical Assoc, 2007-08-15)

Objective: To compare results of treatment with temozolomide or dacarbazine, in combination with an anthracycline, in dogs with relapsed or refractory lymphoma. Design: Nonrandomized, controlled clinical trial. Animals: ...

Use of an axial pattern flap and nictitans to reconstruct medial eyelids and canthus in a dog

Jacobi, Susan; Stanley, Bryden J.; Petersen-Jones, Simon; Dervisis, Nikolaos G.; Dominguez, Pedro A. (Blackwell Publishing, 2008-11-01)

A 10-year-old male neutered Boxer presented with recurrence of a mast cell tumor at the right medial canthal area. Following excision including 2 cm margins, the medial one-half of the upper and lower eyelids and the medial ...

Measurement of serum carboxyterminal cross-linked telopeptide of type I collagen concentration in dogs with osteosarcoma

Hintermeister, John G.; Jones, Pamela D.; Hoffmann, Walter E.; Siegel, Arthur M.; Dervisis, Nikolaos G.; Kitchell, Barbara E. (Amer Veterinary Medical Assoc, 2008-11-01)

Objective—To evaluate the usefulness of carboxyterminal cross-linked telopeptide of type I collagen (ICTP) concentrations for screening dogs for the presence of osteosarcoma. Sample Population—32 client-owned dogs with ...

Combined Gemcitabine and Carboplatin Therapy for Carcinomas in Dogs

Dominguez, Pedro A.; Dervisis, Nikolaos G.; Cadile, Casey D.; Sarbu, L.; Kitchell, B. E. (Wiley-Blackwell Publishing, Inc, 2009-01-01)

Background: Response and adverse reactions to combined gemcitabine (GEM) and carboplatin (CARBO) therapy in dogs with carcinomas are not documented. Hypothesis: GEM and CARBO are safe for the treatment of dogs with ...

Tolerability of Gemcitabine and Carboplatin Doublet Therapy in Cats with Carcinomas

Martinez-Ruzafa, I.; Dominguez, Pedro A.; Dervisis, Nikolaos G.; Sarbu, L.; Newman, R. G.; Cadile, Casey D.; Kitchell, Barbara E. (Wiley-Blackwell Publishing, Inc, 2009-05-01)

Background: This study was performed to determine the toxicity of gemcitabine-carboplatin doublet therapy in cats with carcinomas. Hypothesis: Gemcitabine and carboplatin are safe in tumor-bearing cats. Animals: ...

Prevalence of Antibodies to Sarcocystis neurona in Cats From Virginia and Pennsylvania

Hsu, V.; Grant, David C.; Dubey, Jitender P.; Zajac, Anne M.; Lindsay, David S. (American Society of Parasitology, 2010-08)

Sarcocystis neurone, is best known as the causative agent of equine protozoal myeloencephalitis of horses in the Americas. Domestic cats (Felis domesticus) were the first animals described as an intermediate host for S. ...

Safety of concurrent administration of dexrazoxane and doxorubicin in the canine cancer patient

FitzPatrick, W. M.; Dervisis, Nikolaos G.; Kitchell, B. E. (Wiley-Blackwell Publishing, Inc, 2010-12-01)

Doxorubicinmay cause a rare but serious cardiotoxicity. Dexrazoxane is a cardioprotectant drug used to reduce the risk of cardiotoxicity in human patients. In this study, 25 tumour-bearing dogs were treated with concurrent ...

Recommended Guidelines for the Conduct and Evaluation of Prognostic Studies in Veterinary Oncology

Webster, J. D.; Dennis, M. M.; Dervisis, Nikolaos G.; Heller, J.; Bacon, N. J.; Bergman, P. J.; Bienzle, D.; Cassali, G.; Castagnaro, M.; Cullen, J.; Esplin, D. G.; Pena, L.; Goldschmidt, M. H.; Hahn, K. A.; Henry, C. J.; Hellmen, E.; Kamstock, D.; Kirpensteijn, J.; Kitchell, B. E.; Amorim, R. L.; Lenz, S. D.; Lipscomb, T. P.; McEntee, M.; McGill, L. D.; McKnight, C. A.; McManus, P. M.; Moore, A. S.; Moore, P. F.; Moroff, S. D.; Nakayama, H.; Northrup, N. C.; Sarli, G.; Scase, T.; Sorenmo, K.; Schulman, F. Y.; Shoieb, A. M.; Smedley, R. C.; Spangler, W. L.; Teske, E.; Thamm, D. H.; Valli, V. E.; Vernau, W.; von Euler, H.; Withrow, S. J.; Weisbrode, S. E.; Yager, J.; Kiupel, M. (Sage Publications Inc, 2011-01-01)

There is an increasing need for more accurate prognostic and predictive markers in veterinary oncology because of an increasing number of treatment options, the increased financial costs associated with treatment, and the ...

Serological response of cats to experimental besnoitia darlingi and besnoitia neotomofelis infections and prevalence of antibodies to these parasites in cats from Virginia and Pennsylvania

Houk, Alice E.; Rosypal, A. C.; Grant, David C.; Dubey, Jitender P.; Zajac, Anne M.; Yabsley, Michael J.; Lindsay, David S. (American Society of Parasitology, 2011-04)

Besnoitia darlingi and Besnoitia neotomofelis are cyst-forming tissue apicomplexan parasites that use domestic cats (Felis domesticus) as definitive hosts and opossums (Didelphis virginiana) and Southern Plains woodrats ...

Treatment with DAV for Advanced-Stage Hemangiosarcoma in Dogs

Dervisis, Nikolaos G.; Dominguez, Pedro A.; Newman, R. G.; Cadile, Casey D.; Kitchell, B. E. (Amer Animal Hospital Assoc, 2011-05-01)

Hemangiosarcoma (HSA) is an aggressive disease that is fairly common in the dog. The authors evaluated a doxorubicin, dacarbazine, and vincristine (DAV) combination protocol in dogs with nonresectable stage II and stage ...

Evaluation and comparison of outcomes in dogs with periarticular and nonperiarticular histiocytic sarcoma

Klahn, Shawna L.; Kitchell, Barbara E.; Dervisis, Nikolaos G. (Amer Veterinary Medical Assoc, 2011-07-01)

Objective—To evaluate and compare the outcomes of dogs with periarticular histiocytic sarcoma (PAHS) and histiocytic sarcoma of other anatomic locations (non-PAHS) and identify factors associated with outcome for dogs with ...

Canine tonsillar squamous cell carcinoma - a multi-centre retrospective review of 44 clinical cases

Mas, A.; Blackwood, L.; Cripps, P.; Murphy, S.; de Vos, J.; Dervisis, Nikolaos G.; Martano, M.; Polton, G. A. (Wiley-Blackwell, 2011-07-01)

OBJECTIVES: To review the presenting clinical signs, treatment and survival of dogs with tonsillar squamous cell carcinoma and, if possible, to identify useful prognostic indicators. METHODS: Medical records of 44 dogs ...

Determination of Testicular Blood Flow in Camelids Using Vascular Casting and Color Pulsed-Wave Doppler Ultrasonography

Kutzler, Michelle; Tyson, Reid; Grimes, Monica; Timm, Karen (Hindawi, 2011-09-19)

We describe the vasculature of the camelid testis using plastic casting. We also use color pulsed-wave Doppler ultrasonography to measure testicular blood flow and compare the differences between testicular blood flow in ...

Treatment-related toxicities in tumor-bearing cats treated with temozolomide alone or in combination with doxorubicin: a pilot assessment

Gagnon, Jerome; Dervisis, Nikolaos G.; Kitchell, Barbara E. (Sage Publications Ltd, 2012-08-01)

A retrospective study assessing treatment-related toxicities in tumor-bearing cats treated with temozolomide (TMZ) alone or in combination with doxorubicin was conducted. TMZ was administered orally once a day for 5 days ...