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Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors
Successful medicinal chemistry campaigns to discover and optimize sphingosine kinase inhibitors require a robust assay for screening chemical libraries and for determining rank order potencies. Existing assays for these ...
Inhibiting neurotransmitter reuptake
(United States Patent and Trademark Office, 2018-04-17)
This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter ...