Browsing Fralin Life Sciences Institute by Issue Date
Now showing items 21-40 of 755
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GeneTrees: a phylogenomics resource for prokaryotes
(2007-01)The GeneTrees phylogenomics system pursues comparative genomic analyses from the perspective of gene phylogenies for individual genes. The GeneTrees project has the goal of providing detailed evolutionary models for all ... -
MvirDB - a microbial database of protein toxins, virulence factors and antibiotic resistance genes for bio-defence applications
(2007-01)Knowledge of toxins, virulence factors and antibiotic resistance genes is essential for bio-defense applications aimed at identifying 'functional' signatures for characterizing emerging or engineered pathogens. Whereas ... -
PATRIC: The VBI PathoSystems Resource Integration Center
(2007-01)The PathoSystems Resource Integration Center (PATRIC) is one of eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infection Diseases (NIAID) to create a data and analysis resource ... -
Team Science: 2007 Annual Report
(Virginia Bioinformatics Institute, 2007-01-07) -
Pathogens: 2006 Annual Report
(Virginia Bioinformatics Institute, 2007-01-31) -
Plasmids and Rickettsial Evolution: Insight from Rickettsia felis
(PLOS, 2007-03-07)Background The genome sequence of Rickettsia felis revealed a number of rickettsial genetic anomalies that likely contribute not only to a large genome size relative to other rickettsiae, but also to phenotypic oddities ... -
e-Connections, vol. 2, no. 1; Spring 2007
(Virginia Bioinformatics Institute, Virginia Tech, 2007-04-03) -
Bayesian estimation of genetic parameters for multivariate threshold and continuous phenotypes and molecular genetic data in simulated horse populations using Gibbs sampling
(2007-05-09)Background Requirements for successful implementation of multivariate animal threshold models including phenotypic and genotypic information are not known yet. Here simulated horse data were used to investigate the ... -
A versatile computational pipeline for bacterial genome annotation improvement and comparative analysis, with Brucella as a use case
(2007-06)We present a bacterial genome computational analysis pipeline, called GenVar. The pipeline, based on the program GeneWise, is designed to analyze an annotated genome and automatically identify missed gene calls and sequence ... -
e-Connections, vol. 2, no. 2; Summer 2007
(Virginia Bioinformatics Institute, Virginia Tech, 2007-07-02) -
Scientific Annual Report 2007
(Virginia Bioinformatics Institute, 2007-07-07) -
e-Connections, vol. 2, no. 3; Fall 2007
(Virginia Bioinformatics Institute, Virginia Tech, 2007-09-26) -
Role of information and communication networks in malaria survival
(2007-10-10)Background Quite often symptoms of malaria go unrecognized or untreated. According to the Multilateral Initiative on Malaria, 70% of the malaria cases that are treated at home are mismanaged. Up to 82% of all malaria ... -
A virtual look at Epstein-Barr virus infection: Biological interpretations
(PLOS, 2007-10-19)The possibility of using computer simulation and mathematical modeling to gain insight into biological and other complex systems is receiving increased attention. However, it is as yet unclear to what extent these techniques ... -
Analysis of Schistosoma mansoni genes shared with Deuterostomia and with possible roles in host interactions
(2007-11-08)Background: Schistosoma mansoni is a blood helminth parasite that causes schistosomiasis, a disease that affects 200 million people in the world. Many orthologs of known mammalian genes have been discovered in this parasite ... -
Detecting epistatic interactions contributing to human gene expression using the CEPH family data
(2007-12-18)It is believed that epistatic interactions among loci contribute to variations in quantitative traits. Several methods are available to detect epistasis using population-based data. However, methods to characterize epistasis ... -
An emerging cyberinfrastructure for biodefense pathogen and pathogen-host data
(2008-01)The NIAID-funded Biodefense Proteomics Resource Center (RC) provides storage, dissemination, visualization and analysis capabilities for the experimental data deposited by seven Proteomics Research Centers (PRCs). The data ... -
A quantitative study of the division cycle of Caulobacter crescentus stalked cells
(2008-01)Progression of a cell through the division cycle is tightly controlled at different steps to ensure the integrity of genome replication and partitioning to daughter cells. From published experimental evidence, we propose ... -
e-Connections, vol. 2, no. 4; Winter 2007
(Virginia Bioinformatics Institute, Virginia Tech, 2008-01-07) -
A rapid conditional enumeration haplotyping method in pedigrees
(2008-01-15)Haplotyping in pedigrees provides valuable information for genetic studies (e.g., linkage analysis and association study). In order to identify a set of haplotype configurations with the highest likelihoods for a large ...
