Now showing items 11-20 of 604
e-Connections, vol. 1, no. 2; Summer 2006
(Virginia Bioinformatics Institute, Virginia Tech, 2006-07-06)
The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei
(Public Library of Science, 2013-09-12)
Burkholderia pseudomallei (Bp), the causative agent of the often-deadly infectious disease melioidosis, contains one of the largest prokaryotic genomes sequenced to date, at 7.2 Mb with two large circular chromosomes (1 ...
Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer
Dependence on the glutamine pathway is increased in advanced breast cancer cell models and tumors regardless of hormone receptor status or function. While 70% of breast cancers are estrogen receptor positive (ER+) and ...
GenomeBlast: a web tool for small genome comparison
Background Comparative genomics has become an essential approach for identifying homologous gene candidates and their functions, and for studying genome evolution. There are many tools available for genome comparisons. ...
Rapidly evolving changes and gene loss associated with host switching in Corynebacterium pseudotuberculosis
Phylogenomics and genome scale positive selection analyses were performed on 29 Corynebacterium pseudotuberculosis genomes that were isolated from different hosts, including representatives of the Ovis and Equi biovars. A ...
Production of Virus-Derived Ping-Pong-Dependent piRNA-like Small RNAs in the Mosquito Soma
(Public Library of Science, 2012-01-05)
The natural maintenance cycles of many mosquito-borne pathogens require establishment of persistent non-lethal infections in the invertebrate host. The mechanism by which this occurs is not well understood, but we have ...
Genetic Reporter System for Positioning of Proteins at the Bacterial Pole
Spatial organization within bacteria is fundamental to many cellular processes, although the basic mechanisms underlying localization of proteins to specific sites within bacteria are poorly understood. The study of protein ...
Bed Bugs and Infectious Disease: A Case for the Arboviruses
Bed bug infestations (Cimicidae; Cimex lectularius) have been increasing worldwide over the last few decades [1,2]. Several factors have been posited to explain this resurgence, including widespread insecticide resistance, ...
Enhanced resistance in Theobroma cacao against oomycete and fungal pathogens by secretion of phosphatidylinositol-3-phosphate-binding proteins
The internalization of some oomycete and fungal pathogen effectors into host plant cells has been reported to be blocked by proteins that bind to the effectors' cell entry receptor, phosphatidylinositol-3-phosphate (PI3P). ...
Evaluation Summary. Four Studies Conducted for the Partnership for a Healthier America's Fruits & Veggies (FNV) Campaign in California and Virginia, 2015-2017
(Department Of Human Nutrition, Foods, And Exercise, 2018-02)
This evaluation summary provides brief descriptions of four studies funded by the Robert Wood Johnson Foundation to evaluate the Partnership for a Healthier America’s (PHA’s) branded FNV (Fruits & Veggies) Campaign that ...