In this work we examine C*-algebras of Toeplitz operators over the unit ball in ℂⁿ and the unit polydisc in ℂ². Toeplitz operators are interesting examples of non-normal operators that generate non-commutative C*-algebras. Moreover, in the nice cases (depending on the geometry of the domain) of algebras of Toeplitz operators we can recover some analogues of the spectral theorem up to compact operators. In this setting, we can capture the index of a Fredholm operator which is a fundamental numerical invariant in Operator Theory.