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dc.contributor.authorZhao, Xinen_US
dc.date.accessioned2014-03-14T20:43:26Z
dc.date.available2014-03-14T20:43:26Z
dc.date.issued2006-08-01en_US
dc.identifier.otheretd-08142006-235542en_US
dc.identifier.urihttp://hdl.handle.net/10919/34534
dc.description.abstractThe electrostatic self-assembly (ESA) method presents an effective application in the field of biosensing due to the uniform nanoscale structure. In previous research, a single mode fiber (SMF) sensor system had been investigated for the thin-film measurement due to the high fringe visibility. However, compared with a SMF sensor system, a multimode fiber (MMF) sensor system is lower-cost and has larger sensing area (the fiber core), providing the potential for higher sensing efficiency.

In this thesis, a multimode fiber-optic sensor has been developed based on extrinsic Fabry-Perot interferometry (EFPI) for the measurement of optical thickness in self-assembled thin film layers as well as for the immunosensing test. The sensor was fabricated by connecting a multimode fiber (MMF) and a silica wafer. A Fabry-Perot cavity was formed by the reflections from the two interfaces of the wafer. The negatively charged silica wafer could be used as the substrate for the thin film immobilization scheme. The sensor is incorporated into the white-light interferometric system. By monitoring the optical cavity length increment, the self-assembled thin film thickness was measured; the immunoreaction between immunoglobulin G (IgG) and anti-IgG was investigated.

en_US
dc.publisherVirginia Techen_US
dc.relation.haspartThesis_Xin_Zhao.pdfen_US
dc.rightsI hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to Virginia Tech or its agents the non-exclusive license to archive and make accessible, under the conditions specified below, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report.en_US
dc.subjectElectrostatic self-assembly (ESA)en_US
dc.subjectFabry-Peroten_US
dc.subjectMultimode Fiber Optic Sensorsen_US
dc.subjectWhite-light Interferometryen_US
dc.subjectBiosensoren_US
dc.titleStudy of Multimode Extrinsic Fabry-Perot Interferometric Fiber Optic Sensor on Biosensingen_US
dc.typeThesisen_US
dc.contributor.departmentElectrical and Computer Engineeringen_US
dc.description.degreeMaster of Scienceen_US
thesis.degree.nameMaster of Scienceen_US
thesis.degree.levelmastersen_US
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen_US
thesis.degree.disciplineElectrical and Computer Engineeringen_US
dc.contributor.committeechairWang, Anboen_US
dc.contributor.committeememberPickrell, Gary R.en_US
dc.contributor.committeememberCooper, Kristie L.en_US
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-08142006-235542/en_US
dc.date.sdate2006-08-14en_US
dc.date.rdate2012-04-06
dc.date.adate2007-03-07en_US


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