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dc.contributor.authorYang, Weien_US
dc.date.accessioned2014-03-14T21:09:31Z
dc.date.available2014-03-14T21:09:31Z
dc.date.issued1995en_US
dc.identifier.otheretd-02132009-172025en_US
dc.identifier.urihttp://hdl.handle.net/10919/37356
dc.description.abstractGoigi complex is a multi-compartmental organelle involved in posttranslational modification and sorting of secretory proteins. We have characterized the distribution in Vero cells of three Golgi cisternal membrane proteins, Sialyltransferase (SialyIT, tansGolgi/TGN), galactosyltransferase(GalT, trans-GolgiffGN), and Nacetylglucosametransferase-l (GlcNAcT-I, medial-Golgi), during the process of Golgi disassembly and reassembly following the addition or removal of drugs. After 1 h nocodazole (microtubule depolymerizer) treatment, SialylT and GalT were found in scattered punctate structures that increased in number over time as less and less of these proteins were found perinuclearly.en_US
dc.format.mediumBTDen_US
dc.publisherVirginia Techen_US
dc.relation.haspartLD5655.V856_1995.Y355.pdfen_US
dc.subject.lccLD5655.V856 1995.Y355en_US
dc.titleStudies on the structural organization of Golgi complexen_US
dc.typeDissertationen_US
dc.contributor.departmentBiochemistry and Anaerobic Microbiologyen_US
thesis.degree.namePhDen_US
thesis.degree.leveldoctoralen_US
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen_US
dc.contributor.committeechairStorrie, B.en_US
dc.contributor.committeememberBender, Patrick K.en_US
dc.contributor.committeememberKeenan, T. W.en_US
dc.contributor.committeememberWalker, R. A.en_US
dc.contributor.committeememberWong, E. A.en_US
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-02132009-172025/en_US
dc.date.sdate2009-02-13en_US
dc.date.rdate2009-02-13
dc.date.adate2009-02-13en_US


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