Infrared spectrometry as a high performance liquid chromatographic detector with application to solvent refined coal products
Brown, Robert Scott
MetadataShow full item record
The development of Infrared Spectrometry as a High Performance Liquid Chromatographic detector is presented. Early work with both a conventional dispersive instrument and a Fourier Transform Infrared (FTIR) Spectrometer is presented coupled via a flow cell to size exclusion chromatography. These were used for the analysis of the non-volatile components produced in the liquefaction of coal. Additional work is presented for the coupling of FTIR to analytical scale normal phase chromatography via a flow cell technique. Analysis of both model mixtures as well as a complex process solvent used in the liquefaction process is discussed. Use of deuterochloroform as an improved IR transparent solvent is demonstrated. Work with microbore (1 mm i.d.) columns coupled with on-line flow cell detection is presented. Modification of the flow cell design for microbore compatability is shown as well as the benefits of microbore columns for fiow cell FTIR. Detection limits as amount injected for both analytical and microbore scale HPLC-FTIR are shown.
- Doctoral Dissertations