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dc.contributor.authorGilley, David Williamen_US
dc.date.accessioned2014-03-14T21:20:49Z
dc.date.available2014-03-14T21:20:49Z
dc.date.issued1990-06-15en_US
dc.identifier.otheretd-10122005-134413en_US
dc.identifier.urihttp://hdl.handle.net/10919/39755
dc.description.abstractThe concept of subcortical dementia predicts higher rates of depressive symptomatology in dementia syndromes with predominant subcortical pathology. This hypothesis was evaluated by comparing the frequency and severity of depressive symptomatology in three diagnostic conditions: Alzheimer's disease (AD) (n=30) I subcortical vascular disease (SVD) (n=30), and Parkinson's disease (PD) (n=30). While AD and PD are prototypical exemplars of cortical and subcortical dementia syndromes respectively, SVD provides a test of the generality of the hypothesis as a subcortical neurodegenerative condition whose pathology is not confined to a single subcortical nucleus. A secondary aim of the study was to compare assessment methods for the ascertainment of depressive symptomatology. Assessment methods included the Hamilton Rating Scale for depression derived from interview with the patient's primary caregiver (HRSCG) and from interview with the patient (HRSEX), and the self-report Geriatric Depression Scale. The severity of current depressive symptomatology across the three neurodegenerative disorders followed a consistent pattern across each method of assessment. Specifically, scores on self-report (GDS) , examiner ratings (HRSEX), and caregiver ratings (HRSCG) of depression were most severe in patients with Parkinson's disease (PD) , intermediate in subcortical vascular disease (SVD), and least severe in Alzheimer's the ascertainment of depressive symptomatology. Assessment methods included the Hamilton Rating Scale for depression derived from interview with the patient's primary caregiver (HRSCG) and from interview with the patient (HRSEX), and the self-report Geriatric Depression Scale. The severity of current depressive symptomatology across the three neurodegenerative disorders followed a consistent pattern across each method of assessment. Specifically, scores on self-report (GDS), examiner ratings (HRSEX), and caregiver ratings (HRSCG) of depression were most severe in patients with Parkinson's disease (PD) , intermediate in subcortical vascular disease (SVD), and least severe in Alzheimer'sen_US
dc.format.mediumBTDen_US
dc.publisherVirginia Techen_US
dc.relation.haspartLD5655.V856_1990.G566.pdfen_US
dc.subjectDepressionen_US
dc.subjectMental Diagnosis.en_US
dc.subject.lccLD5655.V856 1990.G566en_US
dc.titleDepression on cortical and subcortical dementia syndromesen_US
dc.typeDissertationen_US
dc.contributor.departmentPsychologyen_US
dc.description.degreePh. D.en_US
thesis.degree.namePh. D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen_US
thesis.degree.disciplinePsychologyen_US
dc.contributor.committeechairHarrison, David W.en_US
dc.contributor.committeememberOllendick, Thomas H.en_US
dc.contributor.committeememberFranchina, Joseph J.en_US
dc.contributor.committeememberCrawford, Helen J.en_US
dc.contributor.committeememberWilson, Robert S.en_US
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-10122005-134413/en_US
dc.date.sdate2005-10-12en_US
dc.date.rdate2005-10-12
dc.date.adate2005-10-12en_US


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