The application of thin film planar waveguides as a refractive index detector for microscale high performance liquid chromatography
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The research works were devoted to studies of waveguide properties and flow dynamics in a chromatographic situation. It was found that microscale detection is possible. The sensitivity can be enhanced by using the highest propagation mode as the probe, and by selecting a proper refractive index liquid as the solvent carrier. A description of the investigation and the various factors involved in designing and optimizing a planar waveguide for refractive index detection is included. The results provide guidelines for the device as a realistic analytical detector.
- Doctoral Dissertations