A new methodology is proposed to investigate the large-signal stability of interconnected power electronics systems. The approach consists of decoupling the system into a source subsystem and a load subsystem, and stability of the entire system can be analyzed based on investigating the feedback loop formed by the interconnected source/load system. The proposed methodology requires two stages: (1) since the source and the load are unknown nonlinear subsystems, system identification, which consists of isolating each subsystem into a series combination of a linear part and a nonlinear part, must be performed, and (2) stability analysis of the interconnected system is conducted thereafter based on a developed stability criterion suitable for the nonlinear interconnected-block-structure model. Applicability of the methodology is verified through stability analysis of PWM converters and a typical power electronics system.