The effect of acetoacetate, organosulfur compounds and hormones on the activity of the liver mitochondria
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1963-06-05
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Virginia Tech
Abstract
The mitochondrial utilization of a-ketoglutaric and pyruvic acids have been found to be depressed in guinea pig and bovine ketosis. Addition of sodium acetoacetate to the reaction medium resulted in depressed oxidation of pyruvate and 1-ketoglutarate of isolated normal rat liver mitochondria.