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1. The sensitivity obtained even with the free
compounds (except morphine) make gas chromatography
a good technique for trace analysis of drugs in biological
2. For many of the drugs studied the detector response
curves are not linear with sample concentration but
the calibration curves are reproducible if care is
exercised. This makes quantitative analysis feasible
down to 50-100 nanogram levels with proper technique.
3. Long column life is needed for routine analyses.
Those columns employed in this work were used continuously
for over seven months with no appreciable deterioration.