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dc.contributor.authorBlumerich, Celeste Annen_US
dc.date.accessioned2014-03-14T21:39:30Z
dc.date.available2014-03-14T21:39:30Z
dc.date.issued2012-06-21en_US
dc.identifier.otheretd-07062012-155716en_US
dc.identifier.urihttp://hdl.handle.net/10919/43534
dc.description.abstractRecurrent Airway Obstruction (RAO)-affected horses experience bronchoconstriction and airway inflammation in response to inhalation of irritants including hay molds. Steaming hay reduces fungal content, but the effect on the antigenic potential has not been investigated. We tested the hypothesis that RAO-affected horses develop less severe clinical disease when fed steamed versus non-steamed hay and this reduction coincides with decreased hay fungal content. Six RAO-affected horses in clinical remission were divided in two groups and fed steamed or non-steamed hay for 10 days using a two-way cross-over design. Hay was steamed using a commercial hay-steamer. Clinical assessment was performed daily. Full assessment, including airway endoscopy, tracheal mucous scores and maximal change in pleural pressure, was performed on days 1, 5, and 10. Bronchial fluid sampling and cytology were performed on days 1 and 10. Hay core samples were collected pre- and post-steaming and cultured to determine fungal and bacterial concentrations. Statistical analysis was based on data distribution and quantity and performed using SAS®. P-value <0.05 was significant. Steaming significantly decreased the number of bacterial and fungal colony-forming-units in hay. Horses fed non-steamed hay experienced a significant increase in clinical score and a trend towards airway neutrophilia, while parameters were unchanged in horses fed steamed hay. Only horses fed non-steamed hay experienced a significant increase in tracheal mucous score. Horses fed steamed hay gained significantly more weight compared to horses fed non-steamed hay, even though the amount of hay consumed not greater on a dry matter basis. These results indicate that steaming reduces the RAO-affected horseâ s response to hay which coincides with a reduction in viable fungal content of hay.en_US
dc.publisherVirginia Techen_US
dc.relation.haspartBlumerich_CA_T_2012.pdfen_US
dc.rightsI hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to Virginia Tech or its agents the non-exclusive license to archive and make accessible, under the conditions specified below, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report.en_US
dc.subjectRecurrent Airway Obstructionen_US
dc.subjectHayen_US
dc.subjectSteamingen_US
dc.subjectFungusen_US
dc.subjectHorsesen_US
dc.titleComparison of Airway Response in Recurrent Airway Obstruction-Affected Horses Fed Steamed Versus Non-steamed Hayen_US
dc.typeThesisen_US
dc.contributor.departmentVeterinary Medical Sciencesen_US
dc.description.degreeMaster of Scienceen_US
thesis.degree.nameMaster of Scienceen_US
thesis.degree.levelmastersen_US
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen_US
thesis.degree.disciplineVeterinary Medical Sciencesen_US
dc.contributor.committeechairBuechner-Maxwell, Virginia A.en_US
dc.contributor.committeememberPereira, Carolina Riccoen_US
dc.contributor.committeememberHodgson, Jennifer L.en_US
dc.contributor.committeememberScarratt, W. Kenten_US
dc.contributor.committeememberWilson, Katherine E.en_US
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-07062012-155716/en_US
dc.date.sdate2012-07-06en_US
dc.date.rdate2012-07-24
dc.date.adate2012-07-24en_US


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