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dc.contributor.authorRobertson, Mark Grahamen_US
dc.date.accessioned2014-03-14T21:50:19Z
dc.date.available2014-03-14T21:50:19Z
dc.date.issued1987-08-05en_US
dc.identifier.otheretd-11202012-040131en_US
dc.identifier.urihttp://hdl.handle.net/10919/45900
dc.description.abstract

Changes in locomotor rhythms of Mus musculus as a response to combinations of lighting and feeding cues were quantitatively assessed in this study. Time allowed for feeding was varied (3, 5, and 7 hours) to examine effect of different zeitgeber strengths on locomotor pattens. The effect of temporal light/dark cue removal on locomotor rhythms was examined in conjunction with restricted feeding regimes. The potential to use blood glucose levels as a temporal feeding cue was examined by comparing the locomotor rhythms of mice consuming either a high glucose or high starch diet. Blood glucose curves for animals under restricted feeding regimes of 1 and 5 hour lengths were determined for the two diets.

Most of the locomotor activity records from animals in total darkness and a restricted feeding regime contained rhythm splitting. Only the anticipatory component of locomotor activity was synchronized by the 7 hour and 5 hour restricted feeding regimes in total darkness. Mice on a 3 hour restriction regime also exhibited a free run component in locomotor activity. The two experimental diets did not produce statistical differences in plasma glucose concentrations when animals were placed on a 5 hour restricted feeding regime in total darkness, but did when they were placed in a light/dark l2:l2 lighting cycle with a 1 hour feeding regime. The locomotor records indicated that freerunning locomotor components were synchronized only by light/dark transitions, while the anticipatory component was synchronized by food presentation. The results of this study are consistent with a Twoâ Oscillator Model for control of activity rhythms.

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dc.format.mediumBTDen_US
dc.publisherVirginia Techen_US
dc.relation.haspartLD5655.V855_1987.R6225.pdfen_US
dc.subjectRodentsen_US
dc.subject.lccLD5655.V855 1987.R6225en_US
dc.titleEffects of diet composition and length of feeding restriction on the locomotor rhythms of Mus musculusen_US
dc.typeThesisen_US
dc.contributor.departmentZoologyen_US
dc.description.degreeMaster of Scienceen_US
thesis.degree.nameMaster of Scienceen_US
thesis.degree.levelmastersen_US
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen_US
thesis.degree.disciplineZoologyen_US
dc.contributor.committeechairCranford, Jack A.en_US
dc.contributor.committeememberMcNabb, Roger A.en_US
dc.contributor.committeememberWebb, Kenneth E., Jr.en_US
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-11202012-040131/en_US
dc.date.sdate2012-11-20en_US
dc.date.rdate2012-11-20
dc.date.adate2012-11-20en_US


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