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dc.contributor.authorCalderone III, Joseph Anthonyen_US
dc.date.accessioned2014-04-26T08:00:09Z
dc.date.available2014-04-26T08:00:09Z
dc.date.issued2014-04-25en_US
dc.identifier.othervt_gsexam:2706en_US
dc.identifier.urihttp://hdl.handle.net/10919/47723
dc.description.abstractAn environmentally friendly, operationally simple copper-amine catalyst system is disclosed. Using this catalyst system, electron deficient alkenes and alkynes with diverse functional groups are borylated and silylated in high yields and with short reaction times. In the case of electron deficient alkynes the identity of the electron withdrawing group controlled diastereoselectivity. Esters and amides exclusively form E-product, while aldehydes and ketones favor Z-product. Mechanistic insights into the catalytic cycle as well as origin of diastereoselectivity are discussed.en_US
dc.format.mediumETDen_US
dc.publisherVirginia Techen_US
dc.rightsThis Item is protected by copyright and/or related rights. Some uses of this Item may be deemed fair and permitted by law even without permission from the rights holder(s), or the rights holder(s) may have licensed the work for use under certain conditions. For other uses you need to obtain permission from the rights holder(s).en_US
dc.subjectCopper Catalysisen_US
dc.subjectSilylationen_US
dc.subjectBorylationen_US
dc.subjectGreen Chemistryen_US
dc.subjectSynthetic Methodologyen_US
dc.titleBorylations and Silylations of Alkenyl and Alkynyl Carbonyl Compounds Employing a Mild and Environmentally Friendly Cu(II) Catalysten_US
dc.typeThesisen_US
dc.contributor.departmentChemistryen_US
dc.description.degreeMaster of Scienceen_US
thesis.degree.nameMaster of Scienceen_US
thesis.degree.levelmastersen_US
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen_US
thesis.degree.disciplineChemistryen_US
dc.contributor.committeechairSantos, Websteren_US
dc.contributor.committeememberTanko, James M.en_US
dc.contributor.committeememberGandour, Richard D.en_US


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