Now showing items 1-10 of 22
Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB. Yaa Mice
IL6 is a multifunctional cytokine that drives terminal B cell differentiation and secretion of immunoglobulins. IL6 also cooperates with IL21 to promote differentiation of CD4+ T follicular helper cells (TFH). Elevated ...
GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro
(Nature Publishing Group, 2016-10-04)
Mammalian Brain Development is Accompanied by a Dramatic Increase in Bipolar DNA Methylation
(Nature Publishing Group, 2016-09-02)
MetaStorm: A Public Resource for Customizable Metagenomics Annotation
Metagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such ...
Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency
(Nature Publishing Group, 2016-04-27)
Application of genetically engineered (GE) large animals carrying multi-allelic modifications has been hampered by low efficiency in production and extended gestation period compared to rodents. Here, we rapidly generated ...
Soil bacteria as sources of virulence signal providers promoting plant infection by Phytophthora pathogens
(Nature Publishing Group, 2016-09-12)
Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis
Simultaneous multiplex mutation of large gene families using Cas9 has the potential to revolutionize agriculture and plant sciences. The targeting of multiple genomic sites at once raises concerns about the efficiency and ...
Low Complexity Compression and Speed Enhancement for Optical Scanning Holography
(Nature Publishing Group, 2016-10-06)
False positives are statistically inevitable
(Amer Assoc Advancement Science, 2016-02-05)