Now showing items 1-10 of 175
The History of Virginia Holsteins: Richdale Farms
Patient-derived glioblastoma stem cells respond differentially to targeted therapies
(Impact Journals Llc, 2016-12-27)
The dismal prognosis of glioblastoma is, at least in part, attributable to the difficulty in eradicating glioblastoma stem cells (GSCs). However, whether this difficulty is caused by the differential responses of GSCs to ...
Therapeutic Innovations: Tyrosine Kinase Inhibitors in Cancer
Conventional cytotoxic chemotherapy involving DNA-interacting agents and indiscriminate cell death is no longer the future of cancer management. While chemotherapy is not likely to completely disappear from the armamentarium; ...
NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-lambda B signaling
(Impact Journals Llc, 2016-05-31)
Pneumonia Caused by Klebsiella spp. in 46 Horses
BACKGROUND: Klebsiella spp. are implicated as a common cause of bacterial pneumonia in horses, but few reports describe clinical presentation and disease progression. HYPOTHESIS/OBJECTIVES: To describe the signalment, ...
Perineural Injection for Treatment of Root-Signature Signs Associated with Lateralized Disk Material in Five Dogs (2009-2013)
Intervertebral disk disease (IVDD) is common in dogs; cervical IVDD accounts for 13-25% of all cases. Ventral slot decompression provides access to ventral and centrally extruded or protruded disk material. However, ...
Nonessential Role for the NLRP1 Inflammasome Complex in a Murine Model of Traumatic Brain Injury
(Hindawi Publishing Corp, 2016-01-01)
Traumatic brain injury (TBI) elicits the immediate production of proinflammatory cytokines which participate in regulating the immune response. While the mechanisms of adaptive immunity in secondary injury are well ...
Use of bio-loggers to characterize red fox behavior with implications for studies of magnetic alignment responses in free-roaming animals
Background Spontaneous magnetic alignment (SMA), in which animals position their body axis in fixed alignments relative to magnetic field lines, has been shown in several classes of vertebrates and invertebrates. Although ...
Neonatal maternal separation stress elicits lasting DNA methylation changes in the hippocampus of stress-reactive Wistar Kyoto rats
Early-life stress (ELS) can alter neurodevelopment in variable ways, ranging from producing deleterious outcomes to stress resilience. While most ELS studies focus on its harmful effects, recent work by our lab and others ...
Mammalian Brain Development is Accompanied by a Dramatic Increase in Bipolar DNA Methylation
(Nature Publishing Group, 2016-09-02)