Branched Peptide Boronic Acids (BPBAs): A Novel Mode of Binding Towards RNA
Bryson, David I.
Crumpton, Jason B.
Santos, Webster L.
MetadataShow full item record
We report branched peptideboronic acids (BPBAs) that bind to RRE IIB from an on-bead high-throughput screening of a 3.3.4-library (46 656 compounds). We demonstrate that boronic acids are tunable moieties that afford a novel binding mode towards RNA.