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dc.contributorVirginia Tech. School of Biomedical Engineering and Sciencesen_US
dc.contributorUniversity of California, San Diego. Department of Bioengineering and Institute of Engineering in Medicineen_US
dc.contributorVirginia Tech. Department of Biomedical Sciences & Pathobiologyen_US
dc.contributorVirginia Tech. Department of Chemical Engineeringen_US
dc.contributor.authorSun, Chenen_US
dc.contributor.authorOuyang, Mingxingen_US
dc.contributor.authorCao, Zhenningen_US
dc.contributor.authorMa, Saien_US
dc.contributor.authorAlqublan, Hamzehen_US
dc.contributor.authorSriranganathan, Nammalwaren_US
dc.contributor.authorWang, Yingxiaoen_US
dc.contributor.authorLu, Changen_US
dc.date.accessioned2015-04-20T22:22:11Z
dc.date.available2015-04-20T22:22:11Z
dc.date.issued2014-08-08
dc.identifier.citationSun, C., Ouyang, M., Cao, Z., Ma, S., Alqublan, H., Sriranganathan, N., Wang, Y., Lu, C. (2014). Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding. Chemical Communications, 50(78), 11536-11539. doi: 10.1039/C4CC04730C
dc.identifier.issn1359-7345
dc.identifier.urihttp://hdl.handle.net/10919/51723
dc.description.abstractFluorescent protein biosensors are typically implemented via genetic encoding which makes the examination of scarce cell samples impractical. By directly delivering the protein form of the biosensor into cells using electroporation, we detected intracellular molecular activity with the sample size down to ~100 cells with high spatiotemporal resolution.
dc.description.sponsorshipVirginia Tech. Institute for Critical Technology and Applied Science
dc.description.sponsorshipNational Science Foundation (U.S.) - Grant 1016547
dc.description.sponsorshipNational Science Foundation (U.S.) - Grant 0967069
dc.description.sponsorshipNational Science Foundation (U.S.) - Grant 1344298
dc.format.mimetypeapplication/pdfen_US
dc.language.isoen_US
dc.publisherThe Royal Society of Chemistry
dc.rightsCreative Commons Attribution-NonCommercial 3.0 Unported
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/
dc.subjectFluorescence resonance energy transferen_US
dc.subjectBiosensorsen_US
dc.subjectGenetic encodingen_US
dc.titleElectroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encodingen_US
dc.typeArticleen_US
dc.description.notesSupplementary information is included in a separate file
dc.identifier.urlhttp://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc04730c
dc.date.accessed2015-04-16
dc.title.serialChemical Communications
dc.identifier.doihttps://doi.org/10.1039/C4CC04730C
dc.type.dcmitypeTexten_US


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Creative Commons Attribution-NonCommercial 3.0 Unported
License: Creative Commons Attribution-NonCommercial 3.0 Unported