Least-squares finite element methods have become increasingly popular for the approximate solution of first-order systems of partial differential equations. Here, after a brief review of some existing theories, a number ...

Reduced-order models have a number of practical engineering applications for unsteady flows that require either low-dimensional approximations for analysis and control or repeated simulation over a range of parameter values. ...

The flow of fluids with different viscosities, subjected to an interfacial perturbation, can lead to fingering and migration...

Porous surfaces impregnated with a liquid lubricant exhibit minimal contact angle hysteresis with immiscible test liquids, rendering them ideal as self-cleaning materials. Rather than roughening a solid substrate, an ...

Cancer drug delivery remains a formidable challenge due to systemic toxicity and inadequate extravascular transport of nanotherapeutics to cells distal from blood vessels. It is hypothesized that, in absence of an external ...

3D printing by fused deposition modelling (FDM) enables rapid prototyping and fabrication of parts with complex geometries. Unfortunately, most materials suitable for FDM 3D printing are non-degradable, petroleum-based ...

Reversible addition-fragmentation chain transfer (RAFT) polymerization enabled the synthesis of well-defined A-BC-A triblock copolymers containing a synergy of pendant ether and imidazolium sites. The soft central BC block ...

Reversible addition-fragmentation chain transfer (RAFT) polymerization afforded the unprecedented synthesis of well-defined acrylic ABA triblock copolymers with nucleobase-functionalized external blocks and a central ...

Background The clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of the utility of CRISPR–Cas9 for in vivo gene ...

An aromatic peptide amphiphile was designed for delivery of the signaling gas H2S. The peptide self-assembled in water into nanofibers that gelled upon charge screening. The non-toxic gel slowly released H2S over 15 hours, ...