Now showing items 1221-1230 of 1315
Reliability of odor offensiveness quantification using the refined cloth swatch olfactometric technique
(American Society of Agricultural and Biological Engineers, 2001)
The cloth swatch olfactometric technique uses flannel swatches to absorb odors for presentation to a trained human sensory panel. This study examined the reliability of the refined cloth swatch technique used to facilitate ...
Large scale complete genome sequencing and phylodynamic analysis of eastern equine encephalitis virus reveal source-sink transmission dynamics in the United States.
(American Society for Microbiology, 2018-04-04)
Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy.
While gene-directed enzyme prodrug therapy has shown potential as a cancer therapeutic in animal and clinical trials, concerns over the efficacy, selectivity, and safety of gene delivery vehicles have restricted its advance. ...
Phytoestrogen Genistein Up-Regulates Endothelial Nitric Oxide Synthase Expression Via Activation of cAMP Response Element-Binding Protein in Human Aortic Endothelial Cells
(Endocrine Society, 2012-07)
We previously reported that genistein, a phytoestrogen, up-regulates endothelial nitric oxide synthase (eNOS) and prevents hypertension in rats that are independent of estrogen signaling machinery. However, how genistein ...
Insights into the Evolution and Function of Auxin Signaling F-Box Proteins in Arabidopsis thaliana Through Synthetic Analysis of Natural Variants.
The evolution of complex body plans in land plants has been paralleled by gene duplication and divergence within nuclear auxin-signaling networks. A deep mechanistic understanding of auxin signaling proteins therefore may ...
Growth Hormone Stimulates Transcription of the Fibroblast Growth Factor 21 Gene in the Liver through the Signal Transducer and Activator of Transcription 5
(Endocrine Society, 2012-02)
Fibroblast growth factor 21 (FGF21) is a recently discovered metabolic regulator. Interestingly, FGF21 is also known to inhibit Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5) signaling ...
A protein therapeutic modality founded on molecular regulation.
The exquisite specificity of proteins is a key feature driving their application to anticancer therapies. The therapeutic potential of another fundamental property of proteins, their ability to be regulated by molecular ...
New tangles in the auxin signaling web.
Plants use auxin to relay critical information that shapes their growth and development. Auxin perception and transcriptional activation are mediated by the degradation of Aux/IAA repressor proteins. Degradation of Aux/IAAs ...
Evaluation of the phenol-free glycosyl-glucose determination
(American Society for Enology and Viticulture, 2000)
Grape glycosides are, in part, an important source of varietal wine aroma and flavor. Aglycones may be aliphatic residues, monoterpenes, sesquiterpenes, norisoprenoids, or phenolic compounds. Studies were undertaken to ...
Differentiation of Endothia gyrosa and Endothia Parasitica by Disc Electrophoresis of Intramycelial Enzymes and Proteins
(Mycological Society of America, 1982)
Mycelial proteins from seven isolates of Endothia gyrosa and five isolates of E. parasitica were extracted from acetone powders, separated on polyacrylamide gels by disc electrophoresis, and then stained for general proteins, ...