Now showing items 1-10 of 15
The Role of Insulin-like Growth Factor-I and IGF-binding Proteins in Mammary Gland Development
(Virginia Tech, 1998-11-19)
Development of the mammary gland is likely mediated by locally produced growth factors acting in concert with circulating mitogens. To investigate the importance of mammary synthesis of insulin-like growth factor-I (IGF-I) ...
An investigation into hormonal regulation of ovine mammary gland growth during pregnancy
(Virginia Tech, 1985-05-05)
Prepartum, multiparous ewes were randomly assigned to experimental groups and sacrificed at 50(n=5), SO(n=4),115(n=5), and 140(n=4) days of gestation. Serum harvested the week prior to slaughter was assayed for progesterone ...
Ovarian and Growth Hormone Regulation of Mammary Growth and Transcript Abundance in Prepubertal Dairy Heifers
(Virginia Tech, 2009-04-03)
Ovarian secretions and growth hormone (GH) are major endocrine regulators of mammary growth and development in bovine mammary gland; but information on endocrine regulation during early prepubertal period is limited. Our ...
Mechanisms Controlling Ductal Morphogenesis in the Ruminant Mammary Gland
(Virginia Tech, 1998-08-17)
Basic research into the histology, endocrine control, and local regulation of prepuberal ruminant mammogenesis was conducted to provide a better understanding of this important developmental period. Histologic features of ...
Effects of bodyweight and plane of nutrition on mitogenic capacity of mammary extracts in cell culture, mammary growth and development, and protein expression profiles of mammary tissue in Holstein heifers
(Virginia Tech, 2004-12-16)
Mammary gland samples from a large serial-slaughter Holstein heifer nutrition trial were used to determine the effects of stage of development and nutritional management on mitogenic activity of mammary extracts and mammary ...
In vitro milk protein secretion by explants of Holstein bull mammary tissue from two different genetic lines
(Virginia Tech, 1990-02-05)
<p>The ability of mammary tissue from mature Holstein bulls to respond to hormonal stimuli in organ culture to synthesize and secrete milk proteins was studied. Sixteen bulls from the genetic selection and control lines ...
Innate Immune Cells may be Involved in Prepubertal Bovine Mammary Development
(Virginia Tech, 2015-07-09)
Pre-pubertal bovine mammary development involves ductal and stromal tissue changes. In mice, this process is impacted by presence of innate immune cells. Whether or not such immune cells are present or involved in bovine ...
Growth Factor and Extracellular Matrix Regulation of Heifer Mammary Development
(Virginia Tech, 2002-08-02)
The overall objective of this project was to investigate the role of locally derived growth factors and extracellular matrix proteins in regulating prepubertal heifer mammary development. In the first experiment, short-term ...
Histological evaluation of ovine mammary tissue xenografted into cyclosporine treated mice
(Virginia Tech, 1988-02-18)
Xenogeneic transplantation of immortalized bovine mammary epithelial cells
(Virginia Tech, 1994-12-05)
<p>The focus of this research was to investigate the use of an immortalized bovine mammary epithelial cell line as a starting material for xenogeneic transplantation into the mammary glands of immunocompetent recipients. ...