Browsing Virginia-Maryland College of Veterinary Medicine (VMCVM) by Author "AbdelKhalek, Ahmed"
Now showing items 1-5 of 5
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Aryl-alkyl-lysines: Novel agents for treatment of C. difficile infection
(Nature Publishing Group, 2020-03-27)Clostridium difficile infections (CDIs) are a growing health concern worldwide. The recalcitrance of C. difficile spores to currently available treatments and concomitant virulence of vegetative cells has made it imperative ... -
Bacteriological profiling of diphenylureas as a novel class of antibiotics against methicillin-resistant Staphylococcus aureus
(PLoS, 2017-08-10)Bacterial resistance to antibiotics remains an imposing global public health challenge. Of the most serious pathogens, methicillin-resistant Staphylococcus aureus (MRSA) is problematic given strains have emerged that exhibit ... -
In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates
(PLoS, 2016-10-06)Bacterial infections present a serious challenge to healthcare practitioners due to the emergence of resistance to numerous conventional antibacterial drugs. Therefore, new bacterial targets and new antimicrobials are unmet ... -
Repurposing auranofin as an intestinal decolonizing agent for vancomycin-resistant enterococci
(Nature Publishing Group, 2018-05-29)Multidrug-resistant enterococcal pathogens, especially vancomycin-resistant enterococci (VRE), are among the pathogens that require new antibiotic innovation. The colonization of the gut represents a major pathway by which ... -
Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE)
(PLoS, 2018-06-28)Enterococci represent one of the microbial world’s most challenging enigmas. Colonization of the gastrointestinal tract (GIT) of high-risk/immunocompromised patients by enterococci exhibiting resistance to vancomycin (VRE) ...
