Now showing items 1-20 of 795

    • 2012-2018 Strategic Plan for the Virginia-Maryland Regional College of Veterinary Medicine 

      Unknown author (Virginia Tech, 2012-09-30)
      In order to maintain our excellence as one of the nation’s top veterinary colleges, we periodically revisit our goals and progress to formulate a strategic plan. The most recent of these plans was drafted on September 30, ...
    • 30th Annual Research Symposium: Chronic Disease and Aging 

      Unknown author (Virginia-Maryland College of Veterinary Medicine, 2019-11-06)
      Each year, the Virginia-Maryland College of Veterinary Medicine hosts this event to support the College’s mission of providing education to a diverse population of professional and post-graduate students in preparation for ...
    • A 6-Nucleotide Regulatory Motif within the AbcR Small RNAs of Brucella abortus Mediates Host-Pathogen Interactions 

      Sheehan, Lauren M.; Caswell, Clayton C. (American Society for Microbiology, 2017-05)
      In Brucella abortus, two small RNAs (sRNAs), AbcR1 and AbcR2, are responsible for regulating transcripts encoding ABC-type transport systems. AbcR1 and AbcR2 are required for Brucella virulence, as a double chromosomal ...
    • A 7-week-old male Golden Retriever with extreme leukocytosis: A case report 

      Bingham, Emily; Conner, Bobbi; Stern, Jere; Vitalo, Amber; Schaer, Michael (Wiley, 2020-09-27)
      Although neoplasia should be a top concern for extreme leukocytosis in dogs, infectious causes must also be considered to avoid delays in treatment or undue recommendations for humane euthanasia. Blood film review is of ...
    • A History of the Development of Brucella Vaccines 

      Avila-Calderon, Eric Daniel; Lopez-Merino, Ahidé; Sriranganathan, Nammalwar; Boyle, Stephen M.; Contreras-Rodriguez, Araceli (Hindawi Publishing Corporation, 2013)
      Brucellosis is a worldwide zoonosis affecting animal and human health. In the last several decades, much research has been performed to develop safer Brucella vaccines to control the disease mainly in animals. Till now, ...
    • Abdominal ultrasonographic findings at diagnosis of osteosarcoma in dogs and association with treatment outcome 

      Sacornrattana, O.; Dervisis, Nikolaos G.; McNiel, E. A. (Wiley-Blackwell, 2013-09-01)
      The purpose of this study was to describe abdominal ultrasonographic findings present at diagnosis of osteosarcoma (OSA) in dogs and to investigate for associations with treatment outcome. Medical records from 118 dogs ...
    • Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments 

      Greer, Kisha; Basso, Erwin Kristobal Gudenschwager; Kelly, Colin; Cash, Alison; Kowalski, Elizabeth; Cerna, Steven; Ocampo, Collin Tanchanco; Wang, Xia; Theus, Michelle H. (2020-09-21)
      Brain injury resulting from repeated mild traumatic insult is associated with cognitive dysfunction and other chronic co-morbidities. The current study tested the effects of aberrant neurogenesis in a mouse model of repeated ...
    • Achromobacter xylosoxidans in extended semen causes reproductive failure in artificially inseminated sows and gilts 

      Clark, Sherrie G. (2008)
      Achromobacter xylosoxidans, a Pseudomonas-like bacterium, contaminated a boar stud laboratory’s water distillation and delivery system that was used for extension of raw semen for artificial insemination. In sow herds that ...
    • The activation of the IFN beta induction/signaling pathway in porcine alveolar macrophages by porcine reproductive and respiratory syndrome virus is variable 

      Overend, Christopher C.; Cui, Junru; Grubman, Marvin J.; Garmendia, Antonio E. (2017-03)
      Background It has been recognized that the expression of type I interferon (IFN alpha/beta) may be suppressed during infection with porcine reproductive, respiratory syndrome virus (PRRSV). This causes profound negative ...
    • ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics in veterinary practice 

      Smith, Annette N.; Klahn, Shawna; Phillips, Brenda; Parshley, Lisa; Bennett, Peter; Flory, Andi; Calderon, Rosemary (American College of Veterinary Internal Medicine, 2018-05)
      The purpose of this report is to offer a consensus opinion of ACVIM oncology diplomates and technicians on the safe use of cytotoxic chemotherapeutics in veterinary practice. The focus is on minimizing harm to the personnel ...
    • Adenovirus transduction to express human ACE2 causes obesity-specific morbidity in mice, impeding studies on the effect of host nutritional status on SARS-CoV-2 pathogenesis 

      Rai, Pallavi; Chuong, Christina; LeRoith, Tanya; Smyth, James W.; Panov, Julia; Levi, Moshe; Kehn-Hall, Kylene; Duggal, Nisha K.; Lucarelli, James-Weger (Elsevier, 2021-11-01)
      The COVID-19 pandemic has paralyzed the global economy and resulted in millions of deaths globally. People with co-morbidities like obesity, diabetes and hypertension are at an increased risk for severe COVID-19 illness. ...
    • Adrenocortical Challenge Response and Genomic Analyses in Scottish Terriers With Increased Alkaline Phosphate Activity 

      Zimmerman, Kurt L.; Panciera, David L.; Hoeschele, Ina; Monroe, William Edward; Todd, Stephanie Michelle; Werre, Stephen R.; LeRoith, Tanya; Fecteau, Kellie; Lake, Bathilda B. (Frontiers, 2018-10-09)
      Scottish terriers (ST) frequently have increased serum alkaline phosphatase (ALP) of the steroid isoform. Many of these also have high serum concentrations of adrenal sex steroids. The study’s objective was to determine ...
    • Advanced breeding techniques of small ruminants and camelids 

      Clark-Deener, Sherrie (2015-05-14)
      After a producer has gained knowledge and experience with the breeding management of their herd or flock, they may decide to attempt a variety of assisted reproductive techniques. What exactly is included in the category ...
    • Adventitious viruses persistently infect three commonly used mosquito cell lines 

      Weger-Lucarelli, James; Ruckert, Claudia; Grubaugh, Nathan D.; Misencik, Michael J.; Armstrong, Philip M.; Stenglein, Mark D.; Ebel, Gregory D.; Brackney, Doug E. (2018-08)
      Mosquito cell lines have been used extensively in research to isolate and propagate arthropod-borne viruses and understand virus-vector interactions. Despite their utility as an in vitro tool, these cell lines are poorly ...
    • Alantolactone Suppresses Proliferation and the Inflammatory Response in Human HaCaT Keratinocytes and Ameliorates Imiquimod-Induced Skin Lesions in a Psoriasis-Like Mouse Model 

      Chuo, Wen-Ho; Tung, Yu-Tang; Wu, Chao-Liang; Bracci, Nicole R.; Chang, Yu-Kang; Huang, Hung-Yi; Lin, Chi-Chien (MDPI, 2021-06-25)
      Psoriasis is an immune-mediated inflammatory disease that affects 2% to 3% of the world population. Alantolactone, a sesquiterpene lactone, was isolated from Inula helenium and Radix inulae and has several ...
    • Aligned nanofiber topography directs the tenogenic differentiation of mesenchymal stem cells 

      Popielarczyk, Tracee L.; Nain, Amrinder S.; Barrett, Jennifer G. (MDPI, 2017-01-06)
      Tendon is commonly injured, heals slowly and poorly, and often suffers re-injury after healing. This is due to failure of tenocytes to effectively remodel tendon after injury to recapitulate normal architecture, resulting ...
    • Aligning evidence generation and use across health, development, and environment 

      Tallis, Heather; Kreis, Katharine; Olander, Lydia; Ringler, Claudia; Ameyaw, David; Borsuk, Mark E.; Fletschner, Diana; Game, Edward; Gilligan, Daniel O.; Jeuland, Marc; Kennedy, Gina; Masuda, Yuta J.; Mehta, Sumi; Miller, Nicholas; Parker, Megan; Pollino, Carmel; Rajaratnam, Julie; Wilkie, David; Zhang, Wei; Ahmed, Selena; Ajayi, Oluyede C.; Alderman, Harold; Arhonditsis, George; Azevedo, Ines; Badola, Ruchi; Bailis, Rob; Balvanera, Patricia; Barbour, Emily; Bardini, Mark; Barton, David N.; Baumgartner, Jill; Benton, Tim G.; Bobrow, Emily; Bossio, Deborah; Bostrom, Ann; Braimoh, Ademola; Brondizio, Eduardo; Brown, Joe; Bryant, Benjamin P.; Calder, Ryan S. D.; Chaplin-Kramer, Becky; Cullen, Alison; DeMello, Nicole; Dickinson, Katherine L.; Ebi, Kristie L.; Eves, Heather E.; Fanzo, Jessica; Ferraro, Paul J.; Fisher, Brendan; Frongillo, Edward A.; Galford, Gillian; Garrity, Dennis; Gatere, Lydiah; Grieshop, Andrew P.; Grigg, Nicola J.; Groves, Craig; Gugerty, Mary Kay; Hamm, Michael; Hou, Xiaoyue; Huang, Cindy; Imhoff, Marc; Jack, Darby; Jones, Andrew D.; Kelsey, Rodd; Kothari, Monica; Kumar, Ritesh; Lachat, Carl; Larsen, Ashley; Lawrence, Mark; DeClerck, Fabrice; Levin, Phillip S.; Mabaya, Edward; Gibson, Jacqueline MacDonald; McDonald, Robert; Mace, Georgina; Maertens, Ricardo; Mangale, Dorothy; Martino, Robin; Mason, Sara; Mehta, Lyla; Meinzen-Dick, Ruth; Merz, Barbara; Msangi, Siwa; Murray, Grant; Murray, Kris A.; Naude, Celeste E.; Newlands, Nathaniel K.; Nkonya, Ephraim; Peterman, Amber; Petruney, Tricia; Possingham, Hugh; Puri, Jyotsna; Remans, Roseline; Remlinger, Lisa; Ricketts, Taylor H.; Reta, Bedilu; Robinson, Brian E.; Roe, Dilys; Rosenthal, Joshua; Shen, Guofeng; Shindell, Drew; Stewart-Koster, Ben; Sunderland, Terry; Sutherland, William J.; Tewksbury, Josh; Wasser, Heather; Wear, Stephanie; Webb, Chris; Whittington, Dale; Wilkerson, Marit; Wittmer, Heidi; Wood, Benjamin DK K.; Wood, Stephen; Wu, Joyce; Yadama, Gautam; Zobrist, Stephanie (Elsevier, 2019-08-01)
      Although health, development, and environment challenges are interconnected, evidence remains fractured across sectors due to methodological and conceptual differences in research and practice. Aligned methods are needed ...
    • Alleviation of Collagen-Induced Arthritis by Crotonoside through Modulation of Dendritic Cell Differentiation and Activation 

      Lin, Shih-Chao; Lin, Chi-Chien; Li, Shiming; Lin, Wan-Yi; Lehman, Caitlin W.; Bracci, Nicole R.; Tsai, Sen-Wei (MDPI, 2020-11-10)
      Crotonoside, a guanosine analog originally isolated from Croton tiglium, is reported to be a potent tyrosine kinase inhibitor with immunosuppressive effects on immune cells. Due to its potential immunotherapeutic ...
    • Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2–Priming Protease TMPRSS2 

      Azouz, N. P.; Klingler, A. M.; Callahan, Victoria; Akhrymuk, Ivan V.; Elez, K.; Raich, L.; Henry, B. M.; Benoit, J. L.; Benoit, S. W.; Noé, F.; Kehn-Hall, Kylene; Rothenberg, M. E. (2021-01-01)
      Background: Host proteases have been suggested to be crucial for dissemination of MERS, SARS-CoV, and SARS-CoV-2 coronaviruses, but the relative contribution of membrane versus intracellular proteases remains controversial. ...
    • Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure 

      Hrubec, Terry C.; Seguin, R. P.; Xu, L.; Cortopassi, G. A.; Datta, S.; Hanlon, Alexandra L.; Lozano, A. J.; McDonald, V. A.; Healy, C. A.; Anderson, T. C.; Musse, N. A.; Williams, R. T. (Elsevier, 2021-01-01)
      Humans are frequently exposed to Quaternary Ammonium Compounds (QACs). QACs are ubiquitously used in medical settings, restaurants, and homes as cleaners and disinfectants. Despite their prevalence, nothing is known about ...