Now showing items 191-200 of 216
Aligned nanofiber topography directs the tenogenic differentiation of mesenchymal stem cells
Tendon is commonly injured, heals slowly and poorly, and often suffers re-injury after healing. This is due to failure of tenocytes to effectively remodel tendon after injury to recapitulate normal architecture, resulting ...
The Parity-Associated Microenvironmental Niche in the Omental Fat Band Is Refractory to Ovarian Cancer Metastasis
(American Association for Cancer Research, 2013-09-10)
Ovarian cancer is an insidious and aggressive disease of older women, typically undiscovered prior to peritoneal metastasis due to its asymptomatic nature and lack of early detection tools. Epidemiological studies suggest ...
Leaky Gut As a Danger Signal for Autoimmune Diseases
(Frontiers Media Sa, 2017-05-23)
Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells
(PLoS One, 2015-12-08)
Background Recent clinical trials using c-kit+ human cardiac stem cells (CSCs) demonstrated promising results in increasing cardiac function and improving quality of life. However, CSC efficiency is low, likely due to ...
Functional Characterization of Detergent-Decellularized Equine Tendon Extracellular Matrix for Tissue Engineering Applications
Natural extracellular matrix provides a number of distinct advantages for engineering replacement orthopedic tissue due to its intrinsic functional properties. The goal of this study was to optimize a biologically derived ...
Intra-Abdominal Fat Depots Represent Distinct Immunomodulatory Microenvironments: A Murine Model
White adipose tissue (WAT) is a multi-faceted endocrine organ involved in energy storage, metabolism, immune function and disease pathogenesis. In contrast to subcutaneous fat, visceral fat (V-WAT) has been associated with ...
High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity
(Nature Publishing Group, 2015-10-13)
Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis
(The Company of Biologists, 2017)
Eosinophilic esophagitis (EoE) is an allergic disease of the esophagus driven by T cell and eosinophil responses to dietary allergens, resulting in chronic mucosal inflammation. Few spontaneous animal models of esophageal ...