The Kalahari ecosystem is characterized by natural resource conflicts and land-use pressure resulting from intensification of human activities. This paper addresses three issues of concern associated with the Kalahari ecosystem resource management: (i) the major land-use/land cover shifts in the Kalahari ecosystem since 1970 and the resulting pattern in vegetation species composition, cover and density; (ii) the possible explanations for the observed shifts; and (iii) the possible resource conflicts likely to arise.