Now showing items 1-4 of 4

    • Enterobacter cloacae inhibits human norovirus infectivity in gnotobiotic pigs 

      Lei, Shaohua; Samuel, Helen; Twitchell, Erica; Bui, Tammy; Ramesh, Ashwin; Wen, Ke; Weiss, Mariah; Li, Guohua; Yang, Xingdong; Jiang, Xi; Yuan, Lijuan (2016-04-26)
      Human noroviruses (HuNoVs) are the leading cause of epidemic gastroenteritis worldwide. Study of HuNoV biology has been hampered by the lack of an efficient cell culture system. Recently, enteric commensal bacteria ...
    • High Protective Efficacy of Probiotics and Rice Bran against Human Norovirus Infection and Diarrhea in Gnotobiotic Pigs 

      Lei, Shaohua; Ramesh, Ashwin; Twitchell, Erica; Wen, Ke; Bui, Tammy; Weiss, Mariah; Yang, Xingdong; Kocher, Jacob; Li, Guohua; Giri-Rachman, Ernawati; Trang, Nguyen Van; Jiang, Xi; Ryan, Elizabeth P.; Yuan, Lijuan (2016)
      Probiotics have been recognized as vaccine adjuvants and therapeutic agents to treat acute gastroenteritis in children. We previously showed that rice bran (RB) reduced human rotavirus diarrhea in gnotobiotic pigs. Human ...
    • High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity 

      Yang, Xingdong; Twitchell, Erica; Li, Guohua; Wen, Ke; Weiss, Mariah; Kocher, Jacob; Lei, Shaohua; Ramesh, Ashwin; Ryan, Elizabeth P.; Yuan, Lijuan (Nature Publishing Group, 2015-10-13)
      Previously, we showed that rice bran (RB) was able to reduce human rotavirus (HRV) diarrhea in gnotobiotic pigs. Here, we investigated its effect on the growth of diarrhea-reducing probiotic Lactobacillus rhamnosus GG (LGG) ...
    • Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs 

      Twitchell, Erica; Tin, Christine; Wen, Ke; Zhang, Husen; Becker-Dreps, Sylvia; Azcarate-Peril, M. Andrea; Vilchez, Samuel; Li, Guohua; Ramesh, Ashwin; Weiss, Mariah; Lei, Shaohua; Bui, Tammy; Yang, Xingdong; Schultz-Cherry, Stacey; Yuan, Lijuan (2016)
      BACKGROUND: Rotavirus vaccines have poor efficacy in infants from low- and middle-income countries. Gut microbiota is thought to influence the immune response to oral vaccines. Thus, we developed a gnotobiotic (Gn) pig ...