Virginia Tech proposed to the National Science Foundation a comprehensive program to promote and enhance the careers of women faculty in science and engineering. AdvanceVT has four major program elements addressing institutional barriers that have constrained the advancement of women faculty members in the sciences and engineering and targeting institutional culture, practices, and leadership development needs specific to Virginia Tech. These four program elements are institutionalizing change, empowering women as leaders and scholars, increasing the representation of women in science and engineering, and advancing women into faculty careers. A comprehensive portfolio of assessment techniques tracks the impact of individual program activities as well as the program as a whole.