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    • Conformationally constrained paclitaxel analogs and their use as anticancer and anti-Alzheimers agents 

      Emory University; Binghamton University; Virginia Tech Intellectual Properties, Inc.; Kingston, David G. I.; Ganesh, Thota; Synder, James Patrick; Lakdawala, Ami S.; Bane, Susan Lynn (United States Patent and Trademark Office, 2007-12-25)
      Constrained paclitaxel derivatives include a bridge extending from the C-3′ phenyl to either the C4 or -3 positions. Many of the constrained paclitaxel derivatives provide activity comparable or superior to the natural ...