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Now showing items 1-4 of 4

    • Expression of a heterologous protein C in mammary tissue of transgenic animals using a long whey acidic protein promoter 

      The American Red Cross; Virginia Tech Intellectual Properties, Inc.; The United States of America as represented by the Department of Health and Human Services; Drohan, William N.; Velander, William H.; Lubon, Henryk; Hennighausen, Lothar (United States Patent and Trademark Office, 2001-07-17)
      An isolated DNA sequence which regulates the expression of a heterologous gene composed of a mouse whey acidic protein promoter having a length of greater than about 2.4 kb extending upstream from the unique KpnI site in ...
    • Expression of active human factor IX in mammary tissue and of milk non human transgenic mammals 

      The American Red Cross; Virginia Tech Intellectual Properties, Inc.; Drohan, William N.; Velander, William H.; Johnson, John L.; Lubon, Henryk (United States Patent and Trademark Office, 2002-02-05)
      Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention. Transgenic animals ...
    • Polyelectrolyte DNA conjugation and genetic transformation of an animal 

      Virginia Tech Intellectual Properties, Inc.; Velander, William H.; Page, Raymond L.; Johnson, John L. (United States Patent and Trademark Office, 1996-06-04)
      The present invention provides a method of obtaining an organism which has been characterized as having cells containing exogenous genetic material which includes any sequence of DNA that can be distinguished as exogenous ...
    • Treatment of hemophilia with human Factor IX produced in mammary tissue of transgenic mammals 

      The American Red Cross; Virginia Tech Intellectual Properties, Inc.; Drohan, William N.; Velander, William H.; Lubon, Henryk; Johnson, representative, Mary Ann (United States Patent and Trademark Office, 2008-09-02)
      Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention. Transgenic animals ...