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dc.date.accessioned2016-08-24T17:53:52Z
dc.date.available2016-08-24T17:53:52Z
dc.date.issued1989-09-05
dc.identifier.urihttp://hdl.handle.net/10919/72341
dc.description.abstractA method is provided for detecting the presence of C. difficile toxin A. Stool or other appropriate specimen is contacted with a reagent containing an available non-reducing galactose-alpha-1-3-galactosyl structure, which is a specific receptor for toxin A. The reagent may be intact cells, cell membranes, membrane fractions containing the toxin A receptor structure, glycoconjugates, as well as the purified toxin A receptor per se. Binding of toxin A is determined by conventional assay techniques. The method may also be used to isolate and purify toxin A. Conversely, immobilized toxin A is used to detect, isolate, or purify biological materials of interest containing the receptor structure.
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_US
dc.publisherUnited States Patent and Trademark Office
dc.titleMethod of detecting, isolating and purifying clostridium difficile toxin A and its receptors
dc.typePatent
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/52/638/048/0.pdf
dc.date.accessed2016-08-19
dc.type.dcmitypeText
dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.
dc.contributor.inventorWilkins, Tracy D.
dc.contributor.inventorKrivan, Howard C.
dc.date.filed1986-02-11
dc.identifier.applicationnumber6828404
dc.subject.uspc435/7.25
dc.subject.uspcother435/7.32
dc.subject.uspcother435/7.92
dc.subject.uspcother435/34
dc.subject.uspcother435/39
dc.subject.uspcother435/803
dc.subject.uspcother435/842
dc.subject.uspcother436/520
dc.subject.uspcother436/534
dc.subject.uspcother436/829
dc.subject.uspcother530/413
dc.subject.uspcother530/825
dc.subject.cpcG01N33/56911
dc.subject.cpcY10S435/803
dc.subject.cpcY10S435/842
dc.subject.cpcY10S436/829
dc.subject.cpcY10S530/825
dc.type.patenttypeutility
dc.identifier.patentnumber4863852


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