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dc.date.accessioned2016-08-24T17:54:15Zen
dc.date.available2016-08-24T17:54:15Zen
dc.date.issued2001-12-04en
dc.identifier.urihttp://hdl.handle.net/10919/72442en
dc.description.abstractVaccines for diseases caused by normally encapsulated organisms are produced by genetically modifying those organisms by deleting the genes encoding for capsule synthesis or a portion thereof sufficient to produce non-capsulated mutants of the organisms. As an example, a live, attenuated strain of Actinobacillus pleuropneumoniae genetically modified with a large deletion in a chromosomal regions of the DNA which encodes for capsule synthesis is a safe and effective vaccine against swine pleuropneumonia.en
dc.format.mimetypeapplication/pdfen
dc.language.isoen_USen
dc.publisherUnited States Patent and Trademark Officeen
dc.titleRecombinant vaccine for diseases caused by encapsulated organismsen
dc.typePatenten
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/01/260/063/0.pdfen
dc.date.accessed2016-08-19en
dc.type.dcmitypeTexten
dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorInzana, Thomas J.en
dc.contributor.inventorWard, Christineen
dc.date.filed1998-07-15en
dc.identifier.applicationnumber9115824en
dc.subject.uspc424/93.4en
dc.subject.uspcother424/93.2en
dc.subject.uspcother435/252.3en
dc.subject.uspcother435/440en
dc.subject.uspcother435/471en
dc.subject.cpcA61K39/0002en
dc.subject.cpcA61K39/102en
dc.subject.cpcA61K2039/522en
dc.subject.cpcA61K2039/552en
dc.subject.cpcC07K14/285en
dc.subject.cpcY10S424/825en
dc.type.patenttypeutilityen
dc.identifier.patentnumber6326001en


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