Transgenic non-human mammals producing fibrinogen in their milk
The University of North Carolina at Chapel Hill
The American Red Cross
Virginia Tech Intellectual Properties, Inc.
Drohan, William N.
Velander, William H.
Johnson, John L.
MetadataShow full item record
A transgenic, non-human mammalian animal is capable of expressing a heterologous gene for human or other recombinant physiologically functional fibrinogen holoprotein or individual subunit chain polypeptides thereof or a modified or fusion fibrinogen in mammary glands of the animals and secreting the expressed product into a body fluid. Methodology employing such a mammal yields recombinant physiologically functional fibrinogens, subunit chain polypeptides thereof, and modified or fusion fibrinogens.
- Virginia Tech Patents