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dc.date.accessioned2016-08-24T17:54:41Z
dc.date.available2016-08-24T17:54:41Z
dc.date.issued2007-05-22
dc.identifier.urihttp://hdl.handle.net/10919/72561
dc.description.abstractDisclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome. In one embodiment, the method increases hemostasis in a subject having hemophilia A or B, by orally administering to the hemophiliac a therapeutically effective amount of the appropriate clotting factor other than in a liposome, sufficient to induce oral tolerance and supply exogenous clotting factor to the subject.
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_US
dc.publisherUnited States Patent and Trademark Office
dc.titleOral treatment of hemophilia
dc.typePatent
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/18/207/072/0.pdf
dc.date.accessed2016-08-19
dc.type.dcmitypeText
dc.contributor.assigneeThe United States of America as represented by the Department of Health and Human Services
dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.
dc.contributor.inventorVelander, William H.
dc.contributor.inventorMatzinger, Polly
dc.contributor.inventorAlpan, Oral
dc.contributor.inventorKamala, Tirumalai
dc.date.filed2002-08-02
dc.identifier.applicationnumber10485696
dc.subject.uspc435/69.1
dc.subject.uspcother435/320.1
dc.subject.uspcother435/325
dc.subject.uspcother435/455
dc.subject.uspcother514/13.7
dc.subject.uspcother800/4
dc.subject.uspcother800/7
dc.subject.uspcother800/8
dc.subject.uspcother800/14
dc.subject.uspcother800/17
dc.subject.cpcA61K38/36
dc.subject.cpcA61K38/27
dc.subject.cpcA61K38/4846
dc.subject.cpcA61K48/00
dc.subject.cpcC12N2799/022
dc.subject.cpcC12N2799/025
dc.subject.cpcC12N2799/027
dc.type.patenttypeutility
dc.identifier.patentnumber7220718


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