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dc.date.accessioned2016-08-24T17:55:26Zen
dc.date.available2016-08-24T17:55:26Zen
dc.date.issued2015-09-01en
dc.identifier.urihttp://hdl.handle.net/10919/72760en
dc.description.abstractThe present invention provides combinations, for treatment of subjects suffering from or at high risk of developing diseases and disorders involving expression of peroxisome proliferator-activated receptors (PPAR). The combinations include abscisic acid and one other bioactive agent, which together provide synergistic effects toward treatment or blocking of development of the disease or disorder. In exemplary embodiments, a combination of abscisic acid and a thiazolidinedione (TZD) is provided for increased insulin sensitivity and improved (i.e., reduced) obesity-induced inflammation.en
dc.format.mimetypeapplication/pdfen
dc.language.isoen_USen
dc.publisherUnited States Patent and Trademark Officeen
dc.titleMethod of synergistically enhancing the therapeutic efficacy and safety of medication through a combination therapyen
dc.typePatenten
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/81/198/091/0.pdfen
dc.date.accessed2016-08-19en
dc.type.dcmitypeTexten
dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorBassaganya-Riera, Josepen
dc.contributor.inventorGuri, Amir J.en
dc.contributor.inventorHontecillas, Raquelen
dc.date.filed2013-05-30en
dc.identifier.applicationnumber13905888en
dc.subject.uspc1/1en
dc.subject.cpcA23L1/3002en
dc.subject.cpcA61K47/12en
dc.subject.cpcA61K31/19en
dc.subject.cpcA61K31/425en
dc.subject.cpcA61K31/426en
dc.subject.cpcA61K31/4427en
dc.subject.cpcA61K31/4439en
dc.subject.cpcA61K45/06en
dc.subject.cpcA61K2300/00en
dc.type.patenttypeutilityen
dc.identifier.patentnumber9119881en


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