Show simple item record

dc.contributor.authorWilliams, Sarah P.en_US
dc.contributor.authorGillaspy, Glenda E.en_US
dc.contributor.authorPerera, Imara Y.en_US
dc.date.accessioned2017-01-04T22:07:16Z
dc.date.available2017-01-04T22:07:16Z
dc.date.issued2015-02-12en_US
dc.identifier.issn1664-462Xen_US
dc.identifier.urihttp://hdl.handle.net/10919/73942
dc.description.abstractInositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. The focus of this review is on the inositol pyrophosphates, which are a novel group of InsP signaling molecules containing diphosphate or triphosphate chains (i.e., PPx) attached to the inositol ring. These PPx-InsPs are emerging as critical players in the integration of cellular metabolism and stress signaling in non-plante ukaryotes. Most eukaryotes synthesize the precursor molecule, myo-inositol (1,2,3,4,5,6)-hexakisphosphate (InsP6), which can serve as a signaling molecule or as storage compound of inositol, phosphorus, and minerals( referred to as phytic acid). Even though plants produce huge amounts of precursor InsP6 in seeds, almost no attention has been paid to whether PPx-InsPs exist in plants, and if so, what roles these molecules play. Recent work has delineated that Arabidopsis has two genes capable of PP-InsP5 synthesis, and PPx-InsPs have been detected across the plant kingdom. This review will detail the known roles of PPx-InsPs in yeast and animal systems, and provide a description of recent data on the synthesis and accumulation of these novel molecules in plants, and potential roles in signaling.en
dc.format.extent? - ? (12) page(s)en_US
dc.languageEnglishen_US
dc.publisherFrontiers Research Foundationen_US
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349235500002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en_US
dc.rightsCreative Commons Attribution 4.0 International (CC BY 4.0)*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPlant Sciencesen_US
dc.subjectplant inositol signalingen_US
dc.subjectinositol hexakisphosphateen_US
dc.subjectVIPen_US
dc.subjectinositol pyrophosphateen_US
dc.subjectenergy metabolismen_US
dc.subjectXENOPUS-LAEVIS OOCYTESen_US
dc.subjectCYCLIN-CDK COMPLEXen_US
dc.subjectDIPHOSPHOINOSITOL PENTAKISPHOSPHATEen_US
dc.subjectCELL-DEATHen_US
dc.subjectHEXAKISPHOSPHATE KINASEen_US
dc.subjectGUARD-CELLSen_US
dc.subjectSACCHAROMYCES-CEREVISIAEen_US
dc.subjectPHOSPHATE HOMEOSTASISen_US
dc.subjectPOLYPHOSPHATE KINASESen_US
dc.subjectTRANSPORTER ATMRP5en_US
dc.titleBiosynthesis and possible functions of inositol pyrophosphates in plantsen_US
dc.typeArticle - Refereed
dc.description.versionPublished (Publication status)en_US
dc.title.serialFRONTIERS IN PLANT SCIENCEen_US
dc.identifier.doihttps://doi.org/10.3389/fpls.2015.00067
dc.identifier.volume6en_US
pubs.organisational-group/Virginia Tech
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Biochemistry
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Faculty
pubs.organisational-group/Virginia Tech/All T&R Faculty


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Creative Commons Attribution 4.0 International (CC BY 4.0)
License: Creative Commons Attribution 4.0 International (CC BY 4.0)