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dc.contributor.authorLiang, Jiangtaoen_US
dc.contributor.authorCheng, Biaoen_US
dc.contributor.authorZhu, Guodingen_US
dc.contributor.authorWei, Yunen_US
dc.contributor.authorTang, Jianxiaen_US
dc.contributor.authorCao, Junen_US
dc.contributor.authorMa, Yajunen_US
dc.contributor.authorSharakhova, Maria V.en_US
dc.contributor.authorXia, Aien_US
dc.contributor.authorSharakhov, Igor V.en_US
dc.date.accessioned2017-01-05T00:10:30Z
dc.date.available2017-01-05T00:10:30Z
dc.date.issued2016-11-25en_US
dc.identifier.citationParasites & Vectors. 2016 Nov 25;9(1):608
dc.identifier.issn1756-3305en_US
dc.identifier.urihttp://hdl.handle.net/10919/73948
dc.description.abstractBackground Anopheles lesteri and Anopheles sinensis are two major malaria vectors in China and Southeast Asia. They are dramatically different in terms of geographical distribution, host preference, resting habitats, and other traits associated with ecological adaptation and malaria transmission. Both species belong to the Anopheles hyrcanus group, but the extent of genetic differences between them is not well understood. To provide an effective way to differentiate between species and to find useful markers for population genetics studies, we performed a comparative cytogenetic analysis of these two malaria vectors. Results Presented here is a standard cytogenetic map for An. lesteri, and a comparative analysis of chromosome structure and gene order between An. lesteri and An. sinensis. Our results demonstrate that much of the gene order on chromosomes X and 2 was reshuffled between the two species. However, the banding pattern and the gene order on chromosome 3 appeared to be conserved. We also found two new polymorphic inversions, 2Lc and 3Rb, in An. lesteri, and we mapped the breakpoints of these two inversions on polytene chromosomes. Conclusions Our results demonstrate the extent of structural divergence of chromosomes between An. lesteri and An. sinensis, and provide a new taxonomic cytogenetic tool to distinguish between these two species. Polymorphic inversions of An. lesteri could serve as markers for studies of the population structure and ecological adaptations of this major malaria vector.
dc.format.extent? - ? (10) page(s)en_US
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.publisherBiomed Central Ltden_US
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000388533000009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en_US
dc.rightsCreative Commons Attribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectParasitologyen_US
dc.subjectCytogenetic mapen_US
dc.subjectChromosomal inversionsen_US
dc.subjectAnopheles lesterien_US
dc.subjectAnopheles sinensisen_US
dc.subjectGene orderen_US
dc.subjectArm homologyen_US
dc.subjectPolytene chromosomesen_US
dc.subjectHYRCANUS GROUPen_US
dc.subjectCULICIDAEen_US
dc.subjectDIPTERAen_US
dc.subjectCHINAen_US
dc.subjectSEQUENCESen_US
dc.subjectPHOTOMAPen_US
dc.subjectGAMBIAEen_US
dc.titleStructural divergence of chromosomes between malaria vectors Anopheles lesteri and Anopheles sinensisen_US
dc.typeArticle - Refereed
dc.description.versionPublished (Publication status)en_US
dc.rights.holderThe Author(s).
dc.title.serialPARASITES & VECTORSen_US
dc.identifier.doihttps://doi.org/10.1186/s13071-016-1855-0
dc.identifier.volume9en_US
dc.type.dcmitypeText
pubs.organisational-group/Virginia Tech
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Faculty
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Entomology
pubs.organisational-group/Virginia Tech/All T&R Faculty
pubs.organisational-group/Virginia Tech/Faculty of Health Sciences


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Creative Commons Attribution 4.0 International
License: Creative Commons Attribution 4.0 International